Evidence map›Paper›PMID 31114720›Full record

ArticleCureus2019

Induction of the Abscopal Effect with Immunotherapy and Palliative Radiation in Metastatic Head and Neck Squamous Cell Carcinoma: A Case Report and Review of the Literature.

Ashwin Shinde, Jennifer Novak, Morganna L Freeman, Scott Glaser, Arya Amini

Abstract readCase Reports
In one paragraph

Article in Cureus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ashwin ShindeRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Jennifer NovakRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Morganna L FreemanMedical Oncology, City of Hope National Medical Center, Duarte, USA.
Scott GlaserRadiation Oncology, City of Hope National Medical Center, Duarte, USA.
Arya AminiRadiation Oncology, City of Hope National Medical Center, Duarte, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The induction of the abscopal effect using immunotherapy and radiation is under investigation through case reports and institutional studies. We describe a case of the abscopal effect with a combination of ipilimumab, nivolumab, and palliative radiation, in a patient with metastatic head and neck squamous cell carcinoma (mHNSCC).

Indexed as

abscopal effectctla-4head and neck cancerimmunotherapypalliativepd-1 inhibitorquad shotradiation

Identifiers

PMID31114720
PMCPMC6505722

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.