Evidence map›Paper›PMID 31114552›Full record

ReviewFrontiers in microbiology2019

Systems Biology - A Guide for Understanding and Developing Improved Strains of Lactic Acid Bacteria.

Jianming Liu, Siu Hung Joshua Chan, Jun Chen, Christian Solem, Peter Ruhdal Jensen

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  5. Article
  6. Review
  7. Evaluation of Safety and Probiotic Properties ofFood science & nutrition · 2025
    Article
  8. HyperpolarizedMolecules (Basel, Switzerland) · 2024
    Article
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  10. Article
  11. Review
  12. Review
  13. Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jianming LiuNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Siu Hung Joshua ChanDepartment of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, United States.
Jun ChenNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Christian SolemNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Peter Ruhdal JensenNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic Acid Bacteria (LAB) are extensively employed in the production of various fermented foods, due to their safe status, ability to affect texture and flavor and finally due to the beneficial effect they have on shelf-life. More recently, LAB have also gained interest as production hosts for various useful compounds, particularly compounds with sensitive applications, such as food ingredients and therapeutics. As for all industrial microorganisms, it is important to have a good understanding of the physiology and metabolism of LAB in order to fully exploit their potential, and for this purpose, many systems biology approaches are available. Systems metabolic engineering, an approach that combines optimization of metabolic enzymes/pathways at the systems level, synthetic biology as well as

Indexed as

control analysisfood fermentationmetabolic engineeringscreening and selectionstrain development

Identifiers

PMID31114552
PMCPMC6503107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.