Evidence map›Paper›PMID 31114513›Full record

ArticleFrontiers in physiology2019

Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats.

Gaudencio Fernández-Miranda, Tatiana Romero-Garcia, Tarín P Barrera-Lechuga, Martha Mercado-Morales, Angélica Rueda

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  6. Tale of two kinases: Protein kinase A and CaWorld journal of diabetes · 2021
    Review
  7. Stress-driven cardiac calcium mishandling via a kinase-to-kinase crosstalk.Pflugers Archiv : European journal of physiology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gaudencio Fernández-MirandaDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV), Mexico City, Mexico.
Tatiana Romero-GarciaDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV), Mexico City, Mexico.
Tarín P Barrera-LechugaDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV), Mexico City, Mexico.
Martha Mercado-MoralesDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV), Mexico City, Mexico.
Angélica RuedaDepartamento de Bioquímica, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV), Mexico City, Mexico.
Center for Research and Advanced Studies of the National Polytechnic Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome (MetS) has become a global epidemic. MetS is a serious health problem because of its related cardiovascular complications, which include hypertension and delayed heart rate recovery after exercise. The molecular bases of cardiac dysfunction in MetS are still under scrutiny and may be related to anomalies in the activity and expression of key proteins involved in the cardiac excitation-contraction coupling (ECC). The cardiac Ca

Indexed as

calcium mishandlingcalcium sparkscardiomyocytesmetabolic syndromeryanodine bindingryanodine receptorSERCA pump

Identifiers

PMID31114513
PMCPMC6503767
OpenAlexW2943309401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.