Evidence map›Paper›PMID 31114296›Full record

ArticleJournal of pain research2019

A novel PDCD10 gene mutation in cerebral cavernous malformations: a case report and review of the literature.

Weiwei Yu, Haiqiang Jin, Qian You, Ding Nan, Yining Huang

Abstract read
In one paragraph

Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weiwei YuDepartment of Neurology, Peking University First Hospital, Beijing 100034, People's Republic of China.
Haiqiang JinDepartment of Neurology, Peking University First Hospital, Beijing 100034, People's Republic of China.
Qian YouDepartment of Neurology, Peking University First Hospital, Beijing 100034, People's Republic of China.
Ding NanDepartment of Neurology, Peking University First Hospital, Beijing 100034, People's Republic of China.
Yining HuangDepartment of Neurology, Peking University First Hospital, Beijing 100034, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral cavernous malformations (CCMs) are one of the most common types of vascular malformation, which are featured enlarged and irregular small blood vessels. The cavernous cavities are merely composed of a single layer of endothelial cells and lack other support tissues, such as elastic fibers and smooth muscle, which make them elastic. CCMs may develop in sporadic or familial forms with autosomal dominant inheritance. Mutations have been identified in three genes:

Indexed as

cerebral cavernous malformationsframeshift mutationhemorrhagePDCD10 genesubcutaneous nodules

Identifiers

PMID31114296
PMCPMC6497854

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.