ArticleNature communications2019
Coordinated representational reinstatement in the human hippocampus and lateral temporal cortex during episodic memory retrieval.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 102 citations in OpenAlex.
- Volitional learning promotes theta phase coding in the human hippocampus.Proceedings of the National Academy of Sciences of the United States of America · 2021Trial
- Rhythmic stimulation elicits multiple, concurrent neural responses.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Deficits in episodic memory and executive functions in relation to CB1 receptor availability in Parkinson's disease.Journal of Parkinson's disease · 2026Article
- Alpha Oscillations Track the Projection of Reactivated Memories into Conscious Awareness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Hippocampal patterns and associative memory: Distinct intracranial EEG temporal encoding patterns support memory.bioRxiv : the preprint server for biology · 2026Article
- Representational dynamics during extinction of fear memories in the human brain.Nature human behaviour · 2026Article
- Spatiotemporal Dynamics of Language Information Representation within the Left Inferior Parietal Lobule Network: An Intracranial SEEG Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Coordinated hippocampal-entorhinal representations support human context-dependent spatial navigation.PLoS biology · 2025Article
- Involuntary and voluntary memory retrieval relies on distinct neural representations and oscillatory processes.PLoS biology · 2025Article
- Human hippocampal reactivation of amygdala encoding-related gamma patterns during aversive memory retrieval.Nature communications · 2025Article
- Movie-watching evokes ripple-like activity within events and at event boundaries.Nature communications · 2025Article
- Frequency-specific and state-dependent neural responses to brain stimulation.Molecular psychiatry · 2025Article
- Sustained Hippocampal Theta Oscillations Reflect Experience-Dependent Learning in Backward Temporal Order Memory Retrieval.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Memory Boost for Recurring Emotional Events Is Driven by Initial Amygdala Response Promoting Stable Neocortical Patterns across Repetitions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Reinstatement and transformation of memory traces for recognition.Science advances · 2025Article
- Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation.Nature neuroscience · 2025Article
- Spatial Cognitive EEG Feature Extraction and Classification Based on MSSECNN and PCMI.Bioengineering (Basel, Switzerland) · 2024Article
- Maintenance and transformation of representational formats during working memory prioritization.Nature communications · 2024Article
- Embodiment in episodic memory through premotor-hippocampal coupling.Communications biology · 2024Article
- The role of theta and gamma oscillations in item memory, source memory, and memory confidence.Psychophysiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Theoretical models of episodic memory have proposed that retrieval depends on interactions between the hippocampus and neocortex, where hippocampal reinstatement of item-context associations drives neocortical reinstatement of item information. Here, we simultaneously recorded intracranial EEG from hippocampus and lateral temporal cortex (LTC) of epilepsy patients who performed a virtual reality spatial navigation task. We extracted stimulus-specific representations of both item and item-context associations from the time-frequency patterns of activity in hippocampus and LTC. Our results revealed a double dissociation of representational reinstatement across time and space: an early reinstatement of item-context associations in hippocampus preceded a later reinstatement of item information in LTC. Importantly, reinstatement levels in hippocampus and LTC were correlated across trials, and the quality of LTC reinstatement was predicted by the magnitude of phase synchronization between hippocampus and LTC. These findings confirm that episodic memory retrieval in humans relies on coordinated representational interactions within a hippocampal-neocortical network.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.