Evidence map›Paper›PMID 31113899›Full record

ArticlemBio2019

Metabolic Remodeling during Biofilm Development of Bacillus subtilis.

Tippapha Pisithkul, Jeremy W Schroeder, Edna A Trujillo, Ponlkrit Yeesin, David M Stevenson, Tai Chaiamarit, Joshua J Coon, Jue D Wang, Daniel Amador-Noguez

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 163 citations in OpenAlex.

  1. Article
  2. Diversification of biofilm architecture among freshwaterApplied and environmental microbiology · 2026
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  8. FeBiofilm · 2026
    Review
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  13. Indolenine-substituted pyrazole derivative 4e inhibits planktonicAntimicrobial agents and chemotherapy · 2025
    Article
  14. Article
  15. Article
  16. Review
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  19. Article
  20. Adaptive Resistance ofMicroorganisms · 2025
    Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tippapha PisithkulGraduate Program in Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-4118-0792
Jeremy W SchroederDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Edna A TrujilloDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Ponlkrit YeesinDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
David M StevensonDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Tai ChaiamaritCollege of Agricultural & Life Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Joshua J CoonMorgridge Institute for Research, Madison, Wisconsin, USA.
Jue D WangDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Daniel Amador-NoguezDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA amadornoguez@wisc.edu.
University of Wisconsin–Madison · US

Funding

TR&D 2 Metabolic Labels for Ultraplexed Protein Quantification p. 453P41GM108538 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COON, JOSHUA J · 2016 to 2025
$13.1M
TR&D 3: TECHNOLOGY DEVELOPMENT FOR NMR STUDIES OF SMALL MOLECULES (METABOLOMICS, NATURAL PRODUCTS, METABOLITE-PROTEIN INTERACTIONS) pp.537-585 P41GM103399 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 2012 to 2019
$9.4M
900 MHz NMR Spectrometer Biomolecular InvestigationsP41GM066326 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN L · 2002 to 2006
$5.0M
The critical roles of (p)ppGpp in homeostasis and antibiotic tolerance in Gram positive bacteriaR35GM127088 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jue D. Wang · 2018 to 2026
$3.9M
NIGMS NIH HHS P41 GM066326NIGMS NIH HHS P41 GM103399NIGMS NIH HHS P41 GM108538NIGMS NIH HHS R35 GM127088
6 · The paper itself

Abstract

Biofilms are structured communities of tightly associated cells that constitute the predominant state of bacterial growth in natural and human-made environments. Although the core genetic circuitry that controls biofilm formation in model bacteria such as

Indexed as

MetabolismAdaptation, PhysiologicalBacillus subtilisBiofilmsGene Expression ProfilingMetabolomicsProteomicsacetoinBacillus subtilisbiofilmsmetabolismmetabolomicsproteomicstranscriptomics

Identifiers

PMID31113899
PMCPMC6529636
OpenAlexW2946290230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.