ArticleBiomedical engineering online2019
Is there any advantage of using stand-alone cages? A numerical approach.
Article in Biomedical engineering online, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Outcome and complications after two-level Anterior Cervical Discectomy and Fusion (ACDF) with or without plating. A propensity matched cohort study.Brain & spine · 2026Article
- Preclinical evaluation of a 3D-printed porous stand-alone interbody cage for cervical fusion in a sheep model.Journal of orthopaedic surgery and research · 2025Article
- Computational analysis of L4-L5 interspinous process devices and interbody fusion spacers using ceramic and polymeric materials via finite element modeling and artificial intelligence.Scientific reports · 2025Article
- Impact of Habitual Flexion on Bone Formation After Spinal Fusion Surgery: An In Silico Study.JOR spine · 2025Article
- A Muscle-Driven Spine Model for Predictive Simulations in the Design of Spinal Implants and Lumbar Orthoses.Bioengineering (Basel, Switzerland) · 2025Article
- Dataset of Finite Element Models of Normal and Deformed Thoracolumbar Spine.Scientific data · 2024Article
- Article
- Risk Factors for Subsidence Following Anterior Lumbar Interbody Fusion.Global spine journal · 2024Article
- Indirect Decompression in Lumbar Degenerative Pathology: Analysis of Imaging Changes at 48 Hours with One-year Follow-up.The archives of bone and joint surgery · 2024Article
- Screw Osteointegration-Increasing Biomechanical Resistance to Pull-Out Effect.Materials (Basel, Switzerland) · 2023Review
- Comparison of Transforaminal Lumbar Interbody Fusion in the Ambulatory Surgery Center and Traditional Hospital Settings, Part 2: Assessment of Surgical Safety in Medicare Beneficiaries.Journal of personalized medicine · 2023Article
- Comparison of Transforaminal Lumbar Interbody Fusion in the Ambulatory Surgery Center and Traditional Hospital Settings, Part 1: Multi-Center Assessment of Surgical Safety.Journal of personalized medicine · 2023Article
- Article
- Effect of the In Situ Screw Implantation Region and Angle on the Stability of Lateral Lumbar Interbody Fusion: A Finite Element Study.Orthopaedic surgery · 2022Article
- Gene-Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSegment fusion using interbody cages supplemented with pedicle screw fixation is the most common surgery for the treatment of low back pain. However, there is still much controversy regarding the use of cages in a stand-alone fashion. The goal of this work is to numerically compare the influence that each surgery has on lumbar biomechanics.
methodsA non-linear FE model of the whole lumbar spine was developed to compare between two types of cages (OLYS and NEOLIF) with and without supplementary fixation. The motion of the whole spine was analysed and the biomechanical environment of the adjacent segments to the operated one was studied. Moreover, the risk of subsidence of the cages was qualitatively evaluated.
resultsA great ROM reduction occurred when supplementary fixation was used. This stiffening increased the stresses at the adjacent levels. It might be hypothesised that the overloading of these segments could be related with the clinically observed adjacent disc degeneration. Meanwhile, the stand-alone cages allowed for a wider movement, and therefore, the influence of the surgery on adjacent discs was much lower. Regarding the risk of subsidence, the contact pressure magnitude was similar for both intervertebral cage designs and near the value of the maximum tolerable pressure of the endplates.
conclusionsA minimally invasive posterior insertion of an intervertebral cage (OLYS or NEOLIF) was compared using a stand-alone design or adding supplementary fixation. The outcomes of these two techniques were compared, and although stand-alone cage may diminish the risk of disease progression to the adjacent discs, the spinal movement in this case could compromise the vertebral fusion and might present a higher risk of cage subsidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.