ArticleBMC cancer2019
Predictors of distant metastasis in parotid acinic cell carcinoma.
Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- The role of elective neck dissection in parotid acinic cell carcinoma: a systematic review.Oral and maxillofacial surgery · 2026Pooled it
- The 8th AJCC classification is inferior to a new neck stage based on intraparotid lymph node in parotid gland cancer.BMC oral health · 2024Article
- Number of positive lymph nodes affects oncologic outcomes in cN0 mucoepidermoid carcinoma of the major salivary gland.Scientific reports · 2024Article
- Major and minor perineural invasion in salivary gland cancer.Frontiers in oncology · 2024Article
- Intraparotid lymph node metastasis affects distant metastasis in parotid adenoid cystic carcinoma.Scientific reports · 2023Article
- Article
- Optimal surgical procedure for treating early-stage adenoid cystic carcinoma of the breast.Scientific reports · 2023Article
- Number of positive lymph nodes affects outcomes in parotid adenoid cystic carcinoma.Frontiers in oncology · 2023Article
- Metastatic lymph node burden impacts overall survival in submandibular gland cancer.Frontiers in oncology · 2023Article
- Influence of parotid lymph node metastasis on distant metastasis in parotid gland cancer.Frontiers in oncology · 2023Article
- Head and Neck Acinic Cell Carcinoma: A New Grading System Proposal and Diagnostic Utility of NR4A3 Immunohistochemistry.The American journal of surgical pathology · 2022Article
- A Rare Case of Brain Metastasis from Dedifferentiated Acinic Cell Carcinoma of the Parotid Gland and Review of the Literature.Iranian journal of pathology · 2022Article
- Occult neck metastases risk factors and the role of elective neck dissection in cT3-4N0 adenoid cystic carcinoma of the parotid gland.Frontiers in oncology · 2022Article
- Fine needle aspiration of salivary gland carcinomas with high-grade transformation: A multi-institutional study of 22 cases and review of the literature.Cancer cytopathology · 2021Review
- Effect of Blood Transfusion on Short- and Long-Term Outcomes in Oral Squamous Cell Carcinoma Patients Undergoing Free Flap Reconstruction.Frontiers in surgery · 2021Article
- Incidence and Prognostic Significance of PD-L1 Expression in High-Grade Salivary Gland Carcinoma.Frontiers in oncology · 2021Article
- Article
- Acinic cell carcinoma of the parotid gland: from pathogenesis to management: a literature review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Review
- Elective neck dissection versus wait-and-see policy in cT1N0 buccal squamous cell carcinoma.BMC cancer · 2020Article
- Comparison Between Primary and Secondary Pediatric Mucoepidermoid Carcinoma of the Head and Neck.Frontiers in pediatrics · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDistant metastasis (DM) is a common treatment failure pattern in acinic cell carcinoma (AciCC) of the major salivary glands; therefore, the main goal of this study was to analyse the predictors of DM in parotid AciCC.
methodsConsecutive patients with surgically treated parotid AciCC who were followed for at least 5 years were retrospectively reviewed. Data regarding age, sex, TNM stage, pathologic characteristics, surgical treatment, and follow-up examinations were collected and analysed. The primary end-point was DM control (DMC); the DMC survival was calculated from the date of surgery to the date of event or the latest follow-up examination and analysed by the Kaplan-Meier method. Independent prognostic factors were evaluated by the Cox proportional hazards method.
resultsA total of 144 patients were included. Positive intraparotid nodes (IPNs) were noted in 34 (31.8%) patients. High-grade transformation was noted in 12 (8.3%) patients. A total of 83 (57.6%) patients underwent neck dissection, and neck node metastasis was proven in 37 (44.6%, 37/83) patients. The 10-year DMC rate was 86%. The Cox model analysis confirmed IPN metastasis (1.854 [1.061-4.144], p = 0.011) and high-grade transformation (4.219 [1.948-15.553], p < 0.001) as independent predictive factors of the DMC survival.
conclusionIPN metastasis and high-grade transformation are independent prognostic factors of the DMC survival.
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