ArticleBMC genomics2019
Integrated microRNA and transcriptome profiling reveals a miRNA-mediated regulatory network of embryo abortion under calcium deficiency in peanut (Arachis hypogaea L.).
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 79 citations in OpenAlex.
- Non-coding RNAs as central regulators of phytohormone signaling in plant abiotic stress responses.Plant molecular biology · 2026Review
- miRNA-Mediated Regulation ofInternational journal of molecular sciences · 2025Article
- Characterization of tae-miR156(s) and their response to abiotic stress in wheat (Triticum aestivum L.).BMC plant biology · 2024Article
- Multiple strategies, including 6mA methylation, affecting plant alternative splicing in allopolyploid peanut.Plant biotechnology journal · 2024Article
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- Omics-driven advances in the understanding of regulatory landscape of peanut seed development.Frontiers in plant science · 2024Review
- Changes in epigenetic features in legumes under abiotic stresses.The plant genome · 2023Review
- Genome-Wide Identification and Characterization of CDPK Gene Family in Cultivated Peanut (Cells · 2023Article
- Genome-Wide Investigation of Apyrase (APY) Genes in Peanut (International journal of molecular sciences · 2023Article
- Transcriptome sequencing and gene expression analysis revealed early ovule abortion of Paeonia ludlowii.BMC genomics · 2023Article
- Integrated microRNA and transcriptome profiling reveals the regulatory network of embryo abortion in jujube.Tree physiology · 2023Article
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- Molecular cloning and functional characterization of the promoter of a novelFrontiers in plant science · 2023Article
- Analysis of miRNAs responsive to long-term calcium deficiency in tef (Plant direct · 2022Article
- Integrated analysis of the lncRNA/circRNA-miRNA-mRNA expression profiles reveals novel insights into potential mechanisms in response to root-knot nematodes in peanut.BMC genomics · 2022Article
- MicroRNA Mediated Plant Responses to Nutrient Stress.International journal of molecular sciences · 2022Review
- Identification of Key Gene Networks and Deciphering Transcriptional Regulators Associated With Peanut Embryo Abortion Mediated by Calcium Deficiency.Frontiers in plant science · 2022Article
- Roles of non-coding RNAs in the hormonal and nutritional regulation in nodulation and nitrogen fixation.Frontiers in plant science · 2022Review
- Genome-wide identification of germin-like proteins in peanut (Frontiers in plant science · 2022Article
- Genome-Wide Characterization of Ascorbate Peroxidase Gene Family in Peanut (Frontiers in plant science · 2022Article
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPeanut embryo development is a complex process involving a series of gene regulatory pathways and is easily affected by various elements in the soil. Calcium deficiency in the soil induces early embryo abortion in peanut, which provides an opportunity to determine the mechanism underlying this important event. MicroRNA (miRNA)-guided target gene regulation is vital to a wide variety of biological processes. However, whether miRNAs participate in peanut embryo abortion under calcium deficiency has yet to be explored.
resultsIn this study, with the assistance of a recently established platform for genome sequences of wild peanut species, we analyzed small RNAs (sRNAs) in early peanut embryos. A total of 29 known and 132 potential novel miRNAs were discovered in 12 peanut-specific miRNA families. Among the identified miRNAs, 87 were differentially expressed during early embryo development under calcium deficiency and sufficiency conditions, and 117 target genes of the differentially expressed miRNAs were identified. Integrated analysis of miRNAs and transcriptome expression revealed 52 differentially expressed target genes of 20 miRNAs. The expression profiles for some differentially expressed targets by gene chip analysis were consistent with the transcriptome sequencing results. Together, our results demonstrate that seed/embryo development-related genes such as TCP3, AP2, EMB2750, and GRFs; cell division and proliferation-related genes such as HsfB4 and DIVARICATA; plant hormone signaling pathway-related genes such as CYP707A1 and CYP707A3, with which abscisic acid (ABA) is involved; and BR1, with which brassinosteroids (BRs) are involved, were actively modulated by miRNAs during early embryo development.
conclusionsBoth a number of miRNAs and corresponding target genes likely playing key roles in the regulation of peanut embryo abortion under calcium deficiency were identified. These findings provide for the first time new insights into miRNA-mediated regulatory pathways involved in peanut embryo abortion under calcium deficiency.
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