Trial reportThe Gerontologist2020
Personality Moderates Intervention Effects on Cognitive Function: A 6-Week Conversation-Based Intervention.
Trial report in The Gerontologist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01571427 (Conversational Engagement as a Means to Delay Alzheimer's Disease Onset), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Conversational Engagement as a Means to Delay Alzheimer's Disease Onset
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Meta-analyses of personality change from the preclinical to the clinical stages of dementia.Ageing research reviews · 2025Pooled it
- Mental health trajectories after juridical divorce: Does personality matter?Journal of personality · 2023Trial
- Can changes in social contact (frequency and mode) mitigate low mood before and during the COVID-19 pandemic? The I-CONECT project.Journal of the American Geriatrics Society · 2022Trial
- Defining nonresponse to pulmonary rehabilitation by threshold scores for personality traits: a population-based study.ERJ open research · 2026Article
- Association of the Big Five personality traits with cognitive decline: a 24-week multidomain intervention study.Frontiers in psychiatry · 2026Article
- Multimodal EEG and explainable machine learning characterize neuroticism-related neurodynamic heterogeneity in mild cognitive impairment during visuospatial working memory.Frontiers in aging neuroscience · 2026Article
- Who Benefits Most? Personality Traits as Predictors of Identity Intervention Outcomes in Adolescence.Journal of youth and adolescence · 2025Article
- Does Personality Moderate the Efficacy of Physical and Cognitive Training Interventions? A 12-month Randomized Controlled Trial in Older Adults.Personality and individual differences · 2023Article
- Emotional characteristics of socially isolated older adults with MCI using tablet administered NIH toolbox: I-CONECT study.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- The Effects of Sustained Literacy Engagement on Cognition and Sentence Processing Among Older Adults.Frontiers in psychology · 2022Article
- The Internet-Based Conversational Engagement Clinical Trial (I-CONECT) in Socially Isolated Adults 75+ Years Old: Randomized Controlled Trial Protocol and COVID-19 Related Study Modifications.Frontiers in digital health · 2021Article
- Cognitive Intervention Through Photo-Integrated Conversation Moderated by Robots (PICMOR) Program: A Randomized Controlled Trial.Frontiers in robotics and AI · 2021Article
- Responder Analysis of a Multicomponent Non-Pharmacological Intervention (MAKS) for People With Cognitive Impairment in the German Day-Care Study (DeTaMAKS).Frontiers in psychiatry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesSocial isolation is associated with a higher risk of dementia. We previously conducted and showed the efficacy of an intervention which uses conversation (the core component of social interactions) as a tool to enhance cognitive function. We now explore whether cognitive improvements through conversation-based intervention depend on an individual's personality. RESEARCH DESIGN AND
methodsWe reexamined data from a 6-week randomized controlled trial (ClinicalTrials.gov Number: NCT01571427) to determine whether conversation-based intervention effects were moderated by personality traits in 83 older adults (mean age = 80.51 years, 49 cognitively intact, 34 individuals with mild cognitive impairment). The intervention group participated in daily 30-min face-to-face semi-structured conversations with trained interviewers through a web-enabled system for 6 weeks. At baseline, psychosocial questionnaires and a neuropsychological battery were completed.
resultsIntervention group participants with high agreeableness, conscientiousness, and extraversion exhibited significant improvements in language-based executive function tasks beyond changes in the control group (ps < .05). An opposite pattern for delayed recall memory and working memory tasks emerged among highly extraverted participants (ps < .05). DISCUSSION AND IMPLICATIONS: Our exploratory findings suggest the adaptive role of personality traits in conversation-based cognitive interventions may be limited to tasks incorporating a language component, and offer initial evidence for personalized approaches to cognitive health in late life.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.