Evidence map›Paper›PMID 31112448›Full record

ArticleJournal of the American Heart Association2019

Association of a Home Monitoring Program With Interstage and Stage 2 Outcomes.

Monique M Gardner, Laura Mercer-Rosa, Jennifer Faerber, Michael P DiLorenzo, Katherine E Bates, Alyson Stagg, Shobha S Natarajan, Anita Szwast, Stephanie Fuller, Christopher E Mascio and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. What Is in a Name?Brazilian journal of cardiovascular surgery · 2025
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  11. Five decades of Fontan palliation: What have we learned? What should we expect?The Journal of international medical research · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Monique M Gardner1 Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh PA.
Laura Mercer-Rosa2 Division of Cardiology Department of Pediatrics The Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Jennifer Faerber3 Department of Pediatrics The Children's Hospital of Philadelphia Philadelphia PA.
Michael P DiLorenzo4 Division of Pediatric Cardiology Department of Pediatrics New York Presbyterian/Morgan Stanley Children's Hospital Columbia University Irving Medical Center New York NY.
Katherine E Bates5 Division of Pediatric Cardiology Department of Pediatrics and Communicable Diseases C.S. Mott Children's Hospital University of Michigan Medical School Ann Arbor MI.
Alyson Stagg6 Division of Cardiology The Children's Hospital of Philadelphia, and The University of Pennsylvania School of Nursing Philadelphia PA.
Shobha S Natarajan2 Division of Cardiology Department of Pediatrics The Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Anita Szwast2 Division of Cardiology Department of Pediatrics The Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Stephanie Fuller7 Division of Cardiothoracic Surgery The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Christopher E Mascio7 Division of Cardiothoracic Surgery The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Desiree Fleck6 Division of Cardiology The Children's Hospital of Philadelphia, and The University of Pennsylvania School of Nursing Philadelphia PA.
Deborah L Torowicz6 Division of Cardiology The Children's Hospital of Philadelphia, and The University of Pennsylvania School of Nursing Philadelphia PA.
Therese M Giglia2 Division of Cardiology Department of Pediatrics The Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Jonathan J Rome2 Division of Cardiology Department of Pediatrics The Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Chitra Ravishankar2 Division of Cardiology Department of Pediatrics The Children's Hospital of Philadelphia, and Perelman School of Medicine at the University of Pennsylvania Philadelphia PA.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · USColumbia University · USC. S. Mott Children's Hospital · USUniversity of Pittsburgh · US

Funding

Outcome and Right Ventricular Remodeling After Repair of Tetralogy of FallotK01HL125521 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI MERCER-ROSA, LAURA M. · 2015 to 2019
$791k
NHLBI NIH HHS K01 HL125521
6 · The paper itself

Abstract

Background In shunt-dependent, single-ventricle patients, mortality remains high in the interstage period between discharge after neonatal surgery and stage 2 operation. We sought to evaluate the impact of our infant single-ventricle management and monitoring program ( ISVMP ) on interstage mortality and stage 2 outcomes. Methods and Results This retrospective single-center cohort study compared patients enrolled in ISVMP at hospital discharge with historical controls. The relationship of ISVMP to interstage mortality was determined with a bivariate probit model for the joint modeling of both groups, using an instrumental variables approach. We included 166 ISVMP participants (December 1, 2010, to June 30, 2015) and 168 controls (January 1, 2007, to November 30, 2010). The groups did not differ by anatomy, gender, race, or genetic syndrome. Mortality was lower in the ISVMP group (5.4%) versus controls (13%). An ISVMP infant compared with a historical control had an average 29% lower predicted probability of interstage death (adjusted probability: -0.29; 95% CI , -0.52 to -0.057; P=0.015). On stratified analysis, mortality was lower in the hypoplastic left heart syndrome subgroup undergoing Norwood operation (4/84 [4.8%] versus 12/90 [14%], P=0.03) but not in those with initial palliation of shunt only ( P=0.90). ISVMP participants were younger at the time of the stage 2 operation (138 versus 160 days, P<0.001), with no difference in postoperative mortality or length of stay. Conclusions In this single-center study, we report significantly lower interstage mortality for participants with hypoplastic left heart syndrome enrolled in ISVMP . Younger age at stage 2 operation was not associated with postoperative mortality or longer length of stay.

Indexed as

AnthropometryCardiac Surgical ProceduresHome Care ServicesOximetryPalliative CarePredictive Value of TestsVentricular FunctionBiomarkersBody WeightFemaleHeart VentriclesHumansHypoplastic Left Heart SyndromeInfantInfant, NewbornMaleBiomarkersOxygenhypoplastic left heart syndromeinterstage mortalityinterstage periodsingle‐ventricle congenital heart disease

Identifiers

PMID31112448
PMCPMC6585324
OpenAlexW2946316895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.