Evidence map›Paper›PMID 31112447›Full record

ArticleHuman vaccines & immunotherapeutics2019

Neisserial PorB immune enhancing activity and use as a vaccine adjuvant.

Rachel Yuen, Jeff Kuniholm, Christina Lisk, Lee M Wetzler

Open access · hybridAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Role of TLRs as signaling cascades to combat infectious diseases: a review.Cellular and molecular life sciences : CMLS · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Clinical microbiology reviews · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Sexually TransmittedMedicines (Basel, Switzerland) · 2021
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rachel YuenDepartment of Microbiology, Boston University School of Medicine, Boston, MA, USA.
Jeff KuniholmDepartment of Microbiology, Boston University School of Medicine, Boston, MA, USA.
Christina LiskSection of Infectious Diseases, Department of Medicine, Boston Medical Center, Boston, MA, USA.
Lee M WetzlerDepartment of Microbiology, Boston University School of Medicine, Boston, MA, USA.
Boston University · USBoston Medical Center · US

Funding

Neisserial Porins and Antigen Presenting CellsR01AI040944 · NIAID · BOSTON MEDICAL CENTER · PI WETZLER, LEE MARK · 1997 to 2019
$9.3M
NIAID NIH HHS R01 AI040944
6 · The paper itself

Abstract

Our laboratory has focused on Porin B (PorB), an outer membrane protein from

Indexed as

Adjuvants, ImmunologicAnimalsAnimals, Genetically ModifiedAntibodies, BacterialAntigen-Presenting CellsCytokinesFemaleImmunoglobulin GMeningococcal InfectionsMiceMyeloid Differentiation Factor 88Neisseria meningitidisPorinsT-LymphocytesAdjuvants, ImmunologicAntibodies, BacterialCytokinesImmunoglobulin GMyd88 protein, mouseMyeloid Differentiation Factor 88porin protein, NeisseriaPorinsAdjuvantgerminal centerMyD88Neisseria meningitidisPorBTLR

Identifiers

PMID31112447
PMCPMC6930065
OpenAlexW2945224129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.