Evidence map›Paper›PMID 31112444›Full record

Observational studyJournal of speech, language, and hearing research : JSLHR2019

Longitudinal Growth in Single Word Intelligibility Among Children With Cerebral Palsy From 24 to 96 Months of Age: Predicting Later Outcomes From Early Speech Production.

Katherine C Hustad, Ashley Sakash, Phoebe E M Natzke, Aimee Teo Broman, Paul J Rathouz

Abstract readObservational Study
In one paragraph

Observational study in Journal of speech, language, and hearing research : JSLHR, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
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  7. Vocal Characteristics of Children With Cerebral Palsy and Anarthria.Journal of speech, language, and hearing research : JSLHR · 2024
    Article
  8. Efficacy and influencing factors of cervical perivascular sympathectomy in children with cerebral palsy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  9. Article
  10. Vocal Characteristics of Infants at Risk for Speech Motor Involvement: A Scoping Review.Journal of speech, language, and hearing research : JSLHR · 2023
    Article
  11. Article
  12. Developmental Cut-Points for Atypical Speech Intelligibility in Children With Cerebral Palsy.Journal of speech, language, and hearing research : JSLHR · 2023
    Article
  13. Singing and Speaking Ability in Parkinson's Disease and Spinocerebellar Ataxia.Journal of speech, language, and hearing research : JSLHR · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Katherine C HustadDepartment of Communication Sciences and Disorders, University of Wisconsin-Madison.
Ashley SakashWaisman Center, University of Wisconsin-Madison.
Phoebe E M NatzkeWaisman Center, University of Wisconsin-Madison.
Aimee Teo BromanDepartment of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison.
Paul J RathouzWaisman Center, University of Wisconsin-Madison.
University of Wisconsin–Madison · US

Funding

Communication Development in Children with Cerebral PalsyR01DC009411 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine C Hustad · 2008 to 2026
$9.4M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI POLLAK, SETH D · 2016 to 2020
$6.0M
NICHD NIH HHS U54 HD090256NIDCD NIH HHS R01 DC009411
6 · The paper itself

Abstract

Purpose Children with cerebral palsy (CP) are at risk for significant communication problems. Reduced speech intelligibility is common, even for those who do not have speech motor deficits. Development of intelligibility has not been comprehensively quantified in children with CP; as a result, we are currently unable to predict later speech outcomes. Such information would advance treatment decision making. We sought to examine growth in speech intelligibility among children with CP using a prospective longitudinal design, with a focus on age of crossing target intelligibility thresholds, age of greatest intelligibility growth, and how well intelligibility at 36 months predicted intelligibility at 96 months. Method Sixty-nine children with CP were followed longitudinally between 24 and 96 months of age. A total of 566 time points were examined across children ( M = 8.2 time points per child, SD = 2.6). We fitted a nonlinear random effects model for longitudinal observations and then used the fitted model trajectories to generate descriptive analyses of growth. We used results of the model to generate a set of simulations, which we analyzed to determine how well 36-month intelligibility data predicted 96-month data. Results Half of children crossed 25% and 50% intelligibility thresholds at 36 and 49 months of age, respectively. Slightly more than half of children did not reach 75% intelligibility by 96 months of age. Age of crossing 25%, 50%, and 75% intelligibility thresholds was highly negatively correlated with intelligibly at 96 months. Children had the steepest intelligibility growth at 36 months, followed by 48 and 60 months. Intelligibility at 36 months was highly predictive of intelligibility at 96 months. Conclusions The developmental window from 3 to 5 years constitutes a time of rapid growth in speech intelligibility in children with CP. Children who cross intelligibility thresholds of 25%, 50%, and 75% at earlier ages have better outcomes when they are older; early performance is highly predictive of later speech intelligibility outcomes. Children with CP as a group have delayed speech intelligibility development but are still growing through 96 months of age.

Indexed as

Cerebral PalsyChildChild LanguageChild, PreschoolFemaleHumansLongitudinal StudiesMaleProspective StudiesSpeech DisordersSpeech IntelligibilitySpeech Production MeasurementVerbal Learning

Identifiers

PMID31112444
PMCPMC6808366
OpenAlexW2945130088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.