ArticleJournal of the American Heart Association2019
Time-Stratified Case Crossover Study of the Association of Outdoor Ambient Air Pollution With the Risk of Acute Myocardial Infarction in the Context of Seasonal Exposure to the Southeast Asian Haze Problem.
Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Short-term effects of haze exposure on clinical and subclinical cardiovascular indicators among adults in Nanjing.Scientific reports · 2026Article
- Short-term lagged exposure to ambient air pollutants and hospitalization costs among AMI patients: health-economic evidence from a low-pollution Chinese city with DRG/DIP standardized medical payment.Frontiers in public health · 2026Article
- Environmental drivers of vertigo.Environmental health and preventive medicine · 2026Article
- Article
- RETRACTED: Artificial intelligence for emergency medical care.Health care science · 2025Review
- Differential effects of fine particulate matter constituents on acute coronary syndrome onset.Nature communications · 2024Article
- Socioeconomic disadvantage and long-term survival duration in out-of-hospital cardiac arrest patients: A population-based cohort study.Resuscitation plus · 2024Article
- Long-term air pollution exposure is associated with higher incidence of ST-elevation myocardial infarction and in-hospital cardiogenic shock.Scientific reports · 2024Article
- Bayesian Approach to Disease Risk Evaluation Based on Air Pollution and Weather Conditions.International journal of environmental research and public health · 2023Article
- Ambient Air Quality and Emergency Hospital Admissions in Singapore: A Time-Series Analysis.International journal of environmental research and public health · 2022Article
- The short-term effects and burden of particle air pollution on hospitalization for coronary heart disease: a time-stratified case-crossover study in Sichuan, China.Environmental health : a global access science source · 2022Article
- Article
- Leveraging open data to reconstruct the Singapore Housing Index and other building-level markers of socioeconomic status for health services research.International journal for equity in health · 2021Article
- Out-of-hospital cardiac arrest and ambient air pollution: A dose-effect relationship and an association with OHCA incidence.PloS one · 2021Observational
- Associations of socioeconomic factors with cause-specific Mortality and burden of cardiovascular diseases: findings from the vital registration in urban Shanghai, China, during 1974-2015.BMC public health · 2020Article
- Leveraging Machine Learning Techniques and Engineering of Multi-Nature Features for National Daily Regional Ambulance Demand Prediction.International journal of environmental research and public health · 2020Article
- Cardiovascular Disease in the Post-COVID-19 Era - the Impending Tsunami?Heart, lung & circulation · 2020Article
- The Lipid Paradox is present in ST-elevation but not in non-ST-elevation myocardial infarction patients: Insights from the Singapore Myocardial Infarction Registry.Scientific reports · 2020Observational
- Air-Pollution Control in an Emergent Market: Does It Work? Evidence from Romania.International journal of environmental research and public health · 2020Article
- Acute Health Impacts of the Southeast Asian Transboundary Haze Problem-A Review.International journal of environmental research and public health · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Prior studies have demonstrated the association of air pollution with cardiovascular deaths. Singapore experiences seasonal transboundary haze. We investigated the association between air pollution and acute myocardial infarction ( AMI ) incidence in Singapore. Methods and Results We performed a time-stratified case-crossover study on all AMI cases in the Singapore Myocardial Infarction Registry (2010-2015). Exposure on days where AMI occurred (case days) were compared with the exposure on days where AMI did not occur (control days). Control days were chosen on the same day of the week earlier and later in the same month and year. We fitted conditional Poisson regression models to daily AMI incidence to include confounders such as ambient temperature, rainfall, wind-speed, and Pollutant Standards Index. We assessed relationships between AMI incidence and Pollutant Standards Index in the entire cohort and subgroups of individual-level characteristics. There were 53 948 cases. Each 30-unit increase in Pollutant Standards Index was association with AMI incidence (incidence risk ratio [ IRR ] 1.04, 95% CI 1.03-1.06). In the subgroup of ST -segment-elevation myocardial infarction the IRR was 1.00, 95% CI 0.98 to 1.03, while for non-ST-segment-elevation myocardial infarction, the IRR was 1.08, 95% CI 1.05 to 1.10. Subgroup analyses showed generally significant. Moderate/unhealthy Pollutant Standards Index showed association with AMI occurrence with IRR 1.08, 95% CI 1.05 to 1.11 and IRR 1.09, 95% CI 1.01 to 1.18, respectively. Excess risk remained elevated through the day of exposure and for >2 years after. Conclusions We found an effect of short-term air pollution on AMI incidence, especially non-ST-segment-elevation myocardial infarction and inpatient AMI . These findings have public health implications for primary prevention and emergency health services during haze.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.