Evidence map›Paper›PMID 31112373›Full record

ArticleCancer medicine2019

Nomograms for predicting long-term overall survival and cancer-specific survival in lip squamous cell carcinoma: A population-based study.

Chuan-Yu Hu, Zhen-Yu Pan, Jin Yang, Xiu-Hong Chu, Jun Zhang, Xue-Jin Tao, Wei-Min Chen, Yuan-Jie Li, Jun Lyu

Abstract read
In one paragraph

Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chuan-Yu HuClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhen-Yu PanClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jin YangClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xiu-Hong ChuDepartment of Nursing, Yeda Hospital, Yantai, China.
Jun ZhangClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xue-Jin TaoStomatology Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wei-Min ChenStomatology Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yuan-Jie LiDepartment of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Jun LyuClinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-2237-8771

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe goal of this study was to establish and validate two nomograms for predicting the long-term overall survival (OS) and cancer-specific survival (CSS) in lip squamous cell carcinoma (LSCC).

methodsThis study selected 4175 patients who were diagnosed with LSCC between 2004 and 2015 in the SEER (Surveillance, Epidemiology, and End Results) database. The patients were allocated randomly to a training cohort and validation cohort. Variables were selected using a backward stepwise method in a Cox regression model. Based on the predictive model with the identified prognostic factors, nomograms were established to predict the 3-, 5-, and 8-year survival OS and CSS rates of LSCC patients. The accuracy of the nomograms was evaluated based on the consistency index (C-index), while their prediction accuracy was evaluated using calibration plots. Decision curve analyses (DCAs) were used to evaluate the performance of our survival model.

resultsThe multivariate analyses demonstrated that age at diagnosis, marital status, sex, race, American Joint Committee on Cancer stage, surgery status, and radiotherapy status were risk factors for both OS and CSS. The C-index, area under the time-dependent receiver operating characteristic curve, and calibration plots demonstrated the good performance of the nomograms. DCAs of both nomograms further showed that they exhibited good 3-, 5-, and 8-year net benefits.

conclusionsWe have developed and validated LSCC prognosis nomograms for OS and CSS for the first time. These nomograms can be valuable tools for clinical practice when clinicians are helping patients to understand their survival risk for the next 3, 5, and 8 years.

Indexed as

AgedCarcinoma, Squamous CellFemaleHumansLip NeoplasmsMaleMiddle AgedPopulation SurveillancePrognosisProportional Hazards ModelsROC CurveSEER Programcancer-specific survivallip squamous cell carcinomanomogramoverall survivalSEER

Identifiers

PMID31112373
PMCPMC6639254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.