Evidence map›Paper›PMID 31112351›Full record

ArticleNMR in biomedicine2019

Detection of lung transplant rejection in a rat model using hyperpolarized [1-

Sarmad Siddiqui, Andreas Habertheuer, Yi Xin, Mehrdad Pourfathi, Jian-Qin Tao, Hooman Hamedani, Stephen Kadlecek, Ian Duncan, Prashanth Vallabhajosyula, Ali Naji and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. IL-27Rα: A Novel Molecular Imaging Marker for Allograft Rejection.International journal of molecular sciences · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sarmad SiddiquiDepartment of Radiology, University of Pennsylvania, PA, USA.ORCID 0000-0002-3601-7539
Andreas HabertheuerDepartment of Surgery, University of Pennsylvania, PA, USA.
Yi XinDepartment of Radiology, University of Pennsylvania, PA, USA.
Mehrdad PourfathiDepartment of Radiology, University of Pennsylvania, PA, USA.
Jian-Qin TaoInstitute for Environmental Medicine, University of Pennsylvania, PA, USA.
Hooman HamedaniDepartment of Radiology, University of Pennsylvania, PA, USA.
Stephen KadlecekDepartment of Radiology, University of Pennsylvania, PA, USA.
Ian DuncanDepartment of Radiology, University of Pennsylvania, PA, USA.
Prashanth VallabhajosyulaDepartment of Surgery, University of Pennsylvania, PA, USA.
Ali NajiDepartment of Surgery, University of Pennsylvania, PA, USA.
Shampa ChatterjeeInstitute for Environmental Medicine, University of Pennsylvania, PA, USA.
Rahim RiziDepartment of Radiology, University of Pennsylvania, PA, USA.

Funding

Improving lung transplant outcomes through the use of imaging in a DBD rat modelR01HL142258 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2018 to 2021
$3.1M
Prediction and assessment of COPD lung volume reduction outcomes with polarized MRIR01HL129805 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2016 to 2019
$3.0M
A New Approach for the Assessment of Pulmonary InflammationR01HL124986 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2015 to 2018
$3.0M
Assessment of Lung Injury with integrated Imaging TechniquesR01HL139066 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2017 to 2020
$2.4M
A Diamond system for real-time metabolic imagingS10OD018478 · OD · UNIVERSITY OF PENNSYLVANIA · PI RIZI, RAHIM R · 2014 to 2014
$2.0M
NHLBI NIH HHS R01 HL124986NHLBI NIH HHS R01 HL129805NHLBI NIH HHS R01 HL139066NHLBI NIH HHS R01 HL142258NIH HHS S10 OD018478
6 · The paper itself

Abstract

The current standard for noninvasive imaging of acute rejection consists of X-ray/CT, which derive their contrast from changes in ventilation, inflammation and edema, as well as remodeling during rejection. We propose the use of hyperpolarized [1-

Indexed as

Molecular ImagingAnimalsBiomarkersCarbon IsotopesGraft RejectionLactic AcidLungLung TransplantationMagnetic Resonance ImagingMaleModels, AnimalOrgan SizePeroxidasePyruvic AcidRats, WistarT-LymphocytesBiomarkersCarbon-13Carbon IsotopesLactic AcidPeroxidasePyruvic Acid[1-13]C pyruvateAllogeneicchemical shift imagingcomputed tomographyhyperpolarized carbon-13lactate-to-pyruvate ratiolung transplantationsyngeneic

Identifiers

PMID31112351
PMCPMC6620127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.