Evidence map›Paper›PMID 31112132›Full record

ArticleeLife2019

The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore.

Josef Fischböck-Halwachs, Sylvia Singh, Mia Potocnjak, Götz Hagemann, Victor Solis-Mezarino, Stephan Woike, Medini Ghodgaonkar-Steger, Florian Weissmann, Laura D Gallego, Julie Rojas and 3 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 99 citations in OpenAlex.

  1. Review
  2. Structure and function of the outer kinetochore.Nature reviews. Molecular cell biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Josef Fischböck-Halwachs *Gene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Sylvia Singh *Gene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Mia Potocnjak *Gene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Götz HagemannGene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Victor Solis-MezarinoGene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Stephan WoikeGene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Medini Ghodgaonkar-StegerGene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Florian WeissmannResearch Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Laura D GallegoMax F Perutz Laboratories, Medical University of Vienna, Vienna, Austria.
Julie RojasLaboratory of Chromosome Biology, Max Planck Institute of Biochemistry, Martinsried, Germany.
Jessica AndreaniInstitute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, Gif-sur-Yvette, France.ORCID 0000-0003-4435-9093
Alwin KöhlerMax F Perutz Laboratories, Medical University of Vienna, Vienna, Austria.
Franz HerzogGene Center Munich, Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.ORCID 0000-0001-8270-1449
Ludwig-Maximilians-Universität München · DEMax Perutz Labs · ATMax Planck Institute of Biochemistry · DEResearch Institute of Molecular Pathology · ATUniversité Paris-Sud · FR

Funding

Austrian Academy of Sciences DOC FellowshipDeutsche Forschungsgemeinschaft Graduate School GRK 1721Deutsche Forschungsgemeinschaft Graduate School Quantitative Biosciences MunichEuropean Research Council 281354 (NPC GENEXPRESS)European Research Council ERC-StG MolStruKT no 638218European Research Council ERC-StG MolStruKT, no. 638218Human Frontier Science Program RGP0008/2015Ludwig-Maximilians-Universität München Excellent Junior grant
6 · The paper itself

Abstract

Kinetochores are macromolecular protein complexes at centromeres that ensure accurate chromosome segregation by attaching chromosomes to spindle microtubules and integrating safeguard mechanisms. The inner kinetochore is assembled on CENP-A nucleosomes and has been implicated in establishing a kinetochore-associated pool of Aurora B kinase, a chromosomal passenger complex (CPC) subunit, which is essential for chromosome biorientation. By performing crosslink-guided in vitro reconstitution of budding yeast kinetochore complexes we showed that the Ame1/Okp1

Indexed as

Protein Interaction MapsKinetochoresProtein BindingSaccharomyces cerevisiae ProteinsSaccharomycetalesSaccharomyces cerevisiae Proteinsaurora Bbiochemistrycell biologychemical biologychemical crosslinkingchromosomal passenger complexchromosome segregationerror correctionfeedback controlkinetochoremass spectrometryS. cerevisiae

Identifiers

PMID31112132
PMCPMC6546395
OpenAlexW2946558174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.