Evidence map›Paper›PMID 31112129›Full record

ArticleeLife2019

Ventral hippocampal projections to the medial prefrontal cortex regulate social memory.

Mary L Phillips, Holly Anne Robinson, Lucas Pozzo-Miller

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 1 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 1 synthesis or guideline pooled it, 205 citations in OpenAlex.

  1. Pooled it
  2. Review
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  9. Article
  10. Impact of early social isolation on social circuits and behavior: relevance to schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Distinct neural dynamics in the ventral hippocampus and medial prefrontal cortex during social information processing.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
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  19. Article
  20. Article

65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mary L PhillipsDepartment of Neurobiology, The University of Alabama at Birmingham, Birmingham, United States.ORCID 0000-0003-4696-1555
Holly Anne RobinsonDepartment of Neurobiology, The University of Alabama at Birmingham, Birmingham, United States.
Lucas Pozzo-MillerDepartment of Neurobiology, The University of Alabama at Birmingham, Birmingham, United States.ORCID 0000-0001-6085-5527
University of Alabama at Birmingham · US

Funding

UAB Research Training Program in Neurobiology of Cognition and Cognitive DisordersT32NS061788 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Farah Dominique Lubin · 2008 to 2026
$4.5M
Role of the Hippocampal-mPFC Pathway in Social Memory Deficits in AutismR01MH118563 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI POZZO-MILLER, LUCAS D · 2019 to 2022
$1.6M
Cortical Spread of Hippocampal Hyperactivity in Rett SyndromeR56NS103089 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI POZZO-MILLER, LUCAS D · 2018 to 2018
$458k
NIH HHS R56-NS103089-01A1NIH HHS T32-NS061788-04NIMH NIH HHS R01 MH118563NINDS NIH HHS R56 NS103089NINDS NIH HHS T32 NS061788
6 · The paper itself

Abstract

Inputs from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC) are implicated in several neuropsychiatric disorders. Here, we show that the vHIP-mPFC projection is hyperactive in the

Indexed as

AnimalsAutism Spectrum DisorderBehavior, AnimalHippocampusHumansMemoryMicePrefrontal CortexPyramidal CellsRett SyndromeTemporal LobeautismMecp2medial prefrontal cortexmouseneuroscienceRett syndromesocial memoryventral hippocampus

Identifiers

PMID31112129
PMCPMC6542587
OpenAlexW2949112906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.