ArticleElectrophoresis2019
Optimization of DNA extraction from dental remains.
Article in Electrophoresis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Review
- Orthodontic Extrusion in Daily Clinical Practice: Management of Fractured or Damaged Anterior Teeth.Journal of personalized medicine · 2025Review
- Review
- A multidisciplinary approach to forensic biological profiling on a single tooth and nail sample.International journal of legal medicine · 2025Article
- Petrous bones versus tooth cementum for genetic analysis of aged skeletal remains.International journal of legal medicine · 2025Article
- A Modified Method for DNA Extraction From Buccal Cells for Genetic Epidemiological Studies Among Children.Cureus · 2024Article
- Dental Radiographic/Digital Radiography Technology along with Biological Agents in Human Identification.Scanning · 2022Review
- A systematic investigation of human DNA preservation in medieval skeletons.Scientific reports · 2020Article
- Thermomechanical DNA extraction from infected dental pulp for next-generation sequencing applications.Journal of oral biology and craniofacial researchArticle
- Forensic DNA analysis of heat-exposed unrestored teeth: Temperature and duration effects.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Efficient DNA extraction procedures is a critical step involved in the process of successful DNA analysis of such samples. Various protocols have been devised for the genomic DNA extraction from human tissues and forensic stains, such as dental tissue that is the skeletal part that better preserves DNA over time. However DNA recovery is low and protocols require labor-intensive and time-consuming step prior to isolating genetic material. Herein, we describe an extremely fast procedure of DNA extraction from teeth compared to classical method. Sixteen teeth of 100-year-old human remains were divided into two groups of 8 teeth and we compared DNA yield, in term of quantity and quality, starting from two different sample preparation steps. Specifically, teeth of group 1 were treated with a classic technique based on several steps of pulverization and decalcification, while teeth of group 2 were processed following a new procedure to withdraw dental pulp. In the next phase, the samples of both group underwent the same procedure of extraction, quantification and DNA profile analysis. Our findings provide an alternative protocol to obtain a higher amount of good quality DNA in a fast time procedure, helpful for forensic and anthropological studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.