ArticleJournal of the International Neuropsychological Society : JINS2019
Visual Object Discrimination Impairment as an Early Predictor of Mild Cognitive Impairment and Alzheimer's Disease.
Article in Journal of the International Neuropsychological Society : JINS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Functional neuroanatomy of musical object processing in Alzheimer's disease and frontotemporal dementia.Brain communications · 2026Article
- Perceptual discrimination of complex objects: Apolipoprotein E e4 gene-dose effects in mid-life.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Object fine-grained discrimination as a sensitive cognitive marker of transentorhinal integrity.Communications biology · 2025Article
- Alzheimer's disease pathophysiology in the Retina.Progress in retinal and eye research · 2024Review
- Design and Feasibility Analysis of a Smartphone-Based Digital Cognitive Assessment Study in the Framingham Heart Study.Journal of the American Heart Association · 2024Article
- Phytochemical Extract from Carica papaya Leaves and Punica granatum Seeds as Therapy Against Cognitive Impairment in a Murine Model.Molecular neurobiology · 2024Article
- Targeting the function of the transentorhinal cortex to identify early cognitive markers of Alzheimer's disease.Cognitive, affective & behavioral neuroscience · 2023Review
- Effects of sex and pro-inflammatory cytokines on context discrimination memory.Behavioural brain research · 2023Article
- Assessing mild cognitive impairment using object-location memory in immersive virtual environments.Hippocampus · 2022Article
- Biomarkers for Alzheimer's Disease in the Current State: A Narrative Review.International journal of molecular sciences · 2022Review
- Olfactory function and discrimination ability in the elderly: a pilot study.The journal of physiological sciences : JPS · 2022Article
- Intrinsic functional connectivity in the default mode network predicts mnemonic discrimination: A connectome-based modeling approach.Hippocampus · 2022Article
- Afferent and Efferent Visual Markers of Alzheimer's Disease: A Review and Update in Early Stage Disease.Frontiers in aging neuroscience · 2020Article
- Identifying cognitive test scores associated with early tau burden in Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Applicability of tactile memory examination as an option to visual- and verbal-based batteries.Dementia & neuropsychologiaArticle
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveDetection of cognitive impairment suggestive of risk for Alzheimer's disease (AD) progression is crucial to the prevention of incipient dementia. This study was performed to determine if performance on a novel object discrimination task improved identification of earlier deficits in older adults at risk for AD.
methodIn total, 135 participants from the 1Florida Alzheimer's Disease Research Center [cognitively normal (CN), Pre-mild cognitive impairment (PreMCI), amnestic mild cognitive impairment (aMCI), and dementia] completed a test of object discrimination and traditional memory measures in the context of a larger neuropsychological and clinical evaluation.
resultsThe Object Recognition and Discrimination Task (ORDT) revealed significant differences between the PreMCI, aMCI, and dementia groups versus CN individuals. Moreover, relative risk of being classified as PreMCI rather than CN increased as an inverse function of ORDT score. DISCUSSION: Overall, the obtained results suggest that a novel object discrimination task improves the detection of very early AD-related cognitive impairment, increasing the window for therapeutic intervention. (JINS, 2019, 25, 688-698).
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