Evidence map›Paper›PMID 31111557›Full record

ArticleJournal of cardiovascular electrophysiology2019

Left atrial effective conducting size predicts atrial fibrillation vulnerability in persistent but not paroxysmal atrial fibrillation.

Steven E Williams, Louisa O'Neill, Caroline H Roney, Justo Julia, Andreas Metzner, Bruno Reißmann, Rahul K Mukherjee, Iain Sim, John Whitaker, Matthew Wright and 3 more

Abstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Impact of effective refractory period personalization on arrhythmia vulnerability in patient-specific atrial computer models.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Applications of multimodality imaging for left atrial catheter ablation.European heart journal. Cardiovascular Imaging · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Challenges Associated with Interpreting Mechanisms of AF.Arrhythmia & electrophysiology review · 2020
    Review
  16. Frontiers in physiology · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Steven E WilliamsDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.ORCID 0000-0002-7266-2084
Louisa O'NeillDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.ORCID 0000-0002-7936-9577
Caroline H RoneyDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.
Justo JuliaDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.ORCID 0000-0003-0914-2876
Andreas MetznerDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Bruno ReißmannDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Rahul K MukherjeeDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.
Iain SimDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.
John WhitakerDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.ORCID 0000-0002-5361-5725
Matthew WrightDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.
Steven NiedererDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.
Christian SohnsDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Mark O'NeillDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.

Funding

British Heart Foundation FS/18/27/33543British Heart Foundation PG/13/37/30280British Heart Foundation WT 203148/Z/16/ZMedical Research Council UK MR/N001877/1Medical Research Council UK Clinical Research Training Fellowship MR/N001877/1Disclosures: None.Wellcome Trust
6 · The paper itself

Abstract

backgroundThe multiple wavelets and functional re-entry hypotheses are mechanistic theories to explain atrial fibrillation (AF). If valid, a chamber's ability to support AF should depend upon the left atrial size, conduction velocity (CV), and refractoriness. Measurement of these parameters could provide a new therapeutic target for AF. We investigated the relationship between left atrial effective conducting size (LA METHODS AND

resultsActivation mapping was performed in patients with paroxysmal (n = 21) and persistent AF (n = 18) undergoing pulmonary vein isolation. Parameters used for calculating LA

conclusionsLA

Indexed as

Atrial Function, LeftCatheter AblationModels, CardiovascularWavelet AnalysisAction PotentialsAdultAgedAged, 80 and overAtrial FibrillationAtrial RemodelingComputer SimulationFemaleHeart RateHumansMaleMiddle Agedatrial fibrillation vulnerabilityconduction velocityleft atrial effective conducting sizerefractoriness

Identifiers

PMID31111557
PMCPMC6746623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.