ArticleRheumatology and therapy2019
Insight into the Quality of Life of Patients with Ankylosing Spondylitis: Real-World Data from a US-Based Life Impact Survey.
Article in Rheumatology and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prevalence of ankylosing spondylitis in a Chinese population: a systematic review and meta-analysis.Rheumatology international · 2020Pooled it
- Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL) questionnaire: translation, cultural adaptation and psychometric validation for use in Iraqi ankylosing spondylitis patients.Clinical rheumatology · 2026Article
- Rethinking arthritis: exploring its types and emerging management strategies.Inflammopharmacology · 2025Review
- Incidence rates of tuberculosis and inflammatory bowel disease in patients with ankylosing spondylitis treated with biologics in Korea.Rheumatology (Oxford, England) · 2025Article
- Psychometric Properties of the Persian Version of the Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL) and Ankylosing Spondylitis Disease Activity Score (ASDAS) Questionnaires: A Cross-Sectional Study.Health science reports · 2025Article
- Long-Term Follow-Up of Patients with Axial Spondyloarthritis in Real-Life Setting: Results from Greece of the Multi-Country Registry Proof Study.Mediterranean journal of rheumatology · 2024Article
- Impact of musculoskeletal joint complaints on quality of life in patients with inflammatory bowel disease: a cross-sectional study.BMJ open · 2024Article
- A concept elicitation study to understand the relationship between sleep and pain in rheumatoid arthritis and axial spondyloarthritis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Educational needs and its associated factors among patients with ankylosing spondylitis in China: a multicenter cross-sectional study.Frontiers in public health · 2024Article
- The International Map of Axial Spondyloarthritis Survey: A US Patient Perspective on Diagnosis and Burden of Disease.ACR open rheumatology · 2023Article
- Qualitative concept elicitation and cognitive debriefing interviews of symptoms, impacts and selected customized PROMISJournal of patient-reported outcomes · 2023Article
- Health-related quality of life among spondyloarthritis and chronic low back pain patients: results from a nationwide population-based survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Influence of Disease Acceptance on the Quality of Life of Patients with Ankylosing Spondylitis - Single Centre Study.Patient preference and adherence · 2023Article
- Gender differences in factors associated with low quality of life and depression in Korean patients with ankylosing spondylitis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Clinical performance of ASAS Health Index in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: real-world evidence from Multicenter Nationwide Registry.Rheumatology international · 2020Observational
- Axial spondyloarthritis 10 years on: still looking for the lost tribe.Rheumatology (Oxford, England) · 2020Review
- Safety Profile of Biologics Used in Rheumatology: An Italian Prospective Pharmacovigilance Study.Journal of clinical medicine · 2020Article
- Unmet need in rheumatology: reports from the Targeted Therapies meeting 2019.Annals of the rheumatic diseases · 2020Review
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe aim to assess the real-world, US patient-reported impact of ankylosing spondylitis (AS) on quality of life (QOL) across physical, discomfort, social, and emotional domains.
methodsDemographic and QOL data were collected from a random sample of patients associated with the Spondylitis Association of America (SAA) from July to December 2017. QOL measures were based on the Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL) questionnaire. The survey evaluated AS impact on the physical domain on the day of survey participation and impact on the discomfort, social, and emotional domains within the week before participation. A 3:1 (male to female) weighting was performed to reflect the reported prevalence of AS in US adults.
resultsOf 820 respondents who completed the survey, 716 self-reported receiving an AS diagnosis from their doctor and were included in this analysis (mean age, 55.5 years; 46.9% male). The mean total EASi-QoL score was 28.9 (weighted); overall, 33.7%, 31.7%, and 34.7% of respondents, respectively, reported a low (EASi-QoL score 0-17), a medium (18-35), and a high (≥ 36) impact of AS on QOL. The physical domain was most impacted; 41.9% of respondents had an EASi-QoL score ≥ 10 (weighted). Women were significantly more likely than men to report a high impact of AS on all QOL domains. Biologic users reported an impact on QOL comparable with the impact on QOL of nonsteroidal anti-inflammatory drug use. AS also impacted lifestyle characteristics, including career choice and sports participation.
conclusionAS negatively impacted all QOL domains analyzed. The incorporation of subjective measures of disease into disease evaluation should be considered.
fundingNovartis Pharmaceuticals Corporation and UCB, Inc. Plain language summary available for this article.
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