Evidence map›Paper›PMID 31111335›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2019

The evaluation on neural status of cervical spinal cord in normal and Hirayama disease using diffusion tensor imaging.

Chi Sun, Shuyi Zhou, Zhongyi Cui, Yuxuan Zhang, Hongli Wang, Jianyuan Jiang, Feizhou Lu, Xiaosheng Ma

Abstract read
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Loss of cervical sagittal alignment worsens the cervical spinal lesions in patients with Hirayama disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chi SunDepartment of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.
Shuyi ZhouDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Zhongyi CuiDepartment of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.
Yuxuan ZhangDepartment of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.
Hongli WangDepartment of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China. wanghongli0212@163.com.
Jianyuan JiangDepartment of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China. jjyfudanspine@126.com.
Feizhou LuDepartment of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.
Xiaosheng MaDepartment of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.

Funding

National Natural Science Foundation of China 81501909National Natural Science Foundation of China 81772388Science and Technology Commission of Shanghai Municipality (CN) 16411964100
6 · The paper itself

Abstract

purposeTo explore the changes in diffusion tensor imaging (DTI) parameters in cervical spinal cord in Hirayama disease (HD) patients and healthy volunteers and to compare these parameters between cervical flexion and neutral positions in HD patients.

methodsSeventeen male patients with HD and eleven healthy young males were included to receive DTI scans in cervical flexion and neutral positions. The FA and ADC values of different levels were measured based on the region of interest drawn on the mid-sagittal plane. The dynamic compressed level's parameters were defined as the lowest and the second lowest FA and the highest and the second highest ADC, respectively. The clinical assessment of patients was obtained using their disabilities of the arm, shoulder and hand (DASH) scores.

resultsFor the HD patients, the FA values in the cervical flexion position were lower and the ADC values were much higher than those in the cervical neutral position. Compared with the controls, the ADC values were significantly higher in the lower levels (C5/6-C7/T1) and the FA values obviously lower at C7/T1 in HD patients in cervical neutral position. The FA and ADC values of the dynamic compressed level in HD patients deviated significantly from the average of the lower levels in controls. Both the FA and ADC values of the dynamic compressed level correlated with the DASH scores (FA, R

conclusionsDTI parameters can support a hypothesis of dynamic cervical flexion compression and noninvasively reveal the neural status of HD patients. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

Cervical CordCervical VertebraeDiffusion Tensor ImagingSpinal Muscular Atrophies of ChildhoodHumansRange of Motion, ArticularApparent diffusion coefficientDiffusion tensor imagingFractional anisotropyHirayama diseaseQuantitative evaluation

Identifiers

PMID31111335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.