Evidence map›Paper›PMID 31111297›Full record

ArticleAIDS and behavior2020

Relationship Type and Use of the Vaginal Ring for HIV-1 Prevention in the MTN 020/ASPIRE Trial.

E Pleasants, T Tauya, K Reddy, B G Mirembe, K Woeber, T Palanee-Phillips, C Zimba, M Atujuna, E T Montgomery, MTN-020/ASPIRE Study Team

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 6 countries.

E PleasantsRTI International, Women's Global Health Imperative, UC Berkeley SPH, 628 Beacon Street, Oakland, CA, 94610, USA. betsypleasants@gmail.com.ORCID http://orcid.org/0000-0001-8435-5682
T TauyaUniversity of Zimbabwe-University of California San Francisco Collaborative Research Program (UZ-UCSF), San Francisco, CA, USA.
K ReddyUniversity of the Witwatersrand, Wits Reproductive Health and HIV Institute (Wits RHI), Johannesburg, South Africa.
B G MirembeMakerere University - Johns Hopkins University Research Collaboration (MU-JHU), Kampala, Uganda.
K WoeberSouth African Medical Research Council (SAMRC), HIV Prevention Research Unit, Cape Town, South Africa.
T Palanee-PhillipsUniversity of the Witwatersrand, Wits Reproductive Health and HIV Institute (Wits RHI), Johannesburg, South Africa.
C ZimbaUNC Project, Tidziwe Centre, Lilongwe, Malawi.
M AtujunaThe Desmond Tutu HIV Foundation, Desmond Tutu HIV Centre (DTHC) at the University of Cape Town, Cape Town, South Africa.
E T MontgomeryRTI International, Women's Global Health Imperative, UC Berkeley SPH, 628 Beacon Street, Oakland, CA, 94610, USA.
MTN-020/ASPIRE Study Team
University of the Witwatersrand · ZADesmond Tutu HIV Foundation · ZARTI International · USSouth African Medical Research Council · ZAPE International (Germany) · DE

Funding

Microbicide Trials NetworkUM1AI068633 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI HILLIER, SHARON L. · 2011 to 2021
$175.0M
University of North Carolina Global HIV Prevention and Treatment Clinical Trials Unit 2024 SupplementUM1AI069423 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, MINA CHRISTINE HOSSEINIPOUR · 2012 to 2026
$71.8M
Statistical and Data Management Center (SDMC): Microbicide Trials NetworkUM1AI068615 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BROWN, ELIZABETH RENATA · 2011 to 2021
$66.5M
The Malawi Clinical Trials UnitUM1AI069518 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JACKY M JENNINGS, TAHA E TAHA · 2012 to 2026
$43.8M
The Johns Hopkins University - Uganda Clinical Trials UnitUM1AI069530 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MARY Glenn Fowler, Philippa Musoke · 2012 to 2026
$34.8M
Wits HIV Research Group CLINICAL TRIAL UNIT (CTU) reapplicationUM1AI069463 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI REES, HELEN, SANNE, IAN MATTHIAS · 2012 to 2025
$31.8M
Laboratory Center (LC): Microbicide Trials NetworkUM1AI106707 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI MELLORS, JOHN W, ROHAN, LISA CENCIA · 2014 to 2021
$27.1M
BIOMEDICAL INFORMATION DEVELOPMENT IN SUB-SAHARAN AFRICAD43TW001081 · FIC · JOHNS HOPKINS UNIVERSITY · PI TAHA, TAHA E · 1998 to 2003
$435k
FIC NIH HHS D43 TW001081National Institute of Allergy and Infectious Diseases UM1AI068615National Institute of Allergy and Infectious Diseases UM1AI068633National Institute of Allergy and Infectious Diseases UM1AI106707NIAID NIH HHS UM1 AI068615NIAID NIH HHS UM1 AI068633NIAID NIH HHS UM1 AI069423NIAID NIH HHS UM1 AI069463NIAID NIH HHS UM1 AI069518NIAID NIH HHS UM1 AI069530NIAID NIH HHS UM1 AI106707
6 · The paper itself

Abstract

Gender roles and imbalances in sexual power contribute to the heightened HIV-1 risk faced by women in Sub-Saharan Africa. This has led prevention research to focus on the development of female controlled methods. Despite the design of products such as vaginal rings to be used autonomously by women, male partners and women's perceptions of relationships influence HIV prevention choices. To understand the influences that male partners and dyadic dynamics had on the use of the Dapivirine Vaginal Ring in the ASPIRE trial, this analysis of qualitative data explored the types of intimate partner relationships that women engaged in. This paper describes how partners facilitated or challenged women's ring use and how women dealt with these challenges within six different types of relationships characterized by power dynamics and commitment levels. We offer insights into how future use of female-initiated HIV prevention products can be promoted through recognition of different relationship types.

Indexed as

Interpersonal RelationsAdministration, IntravaginalAdolescentAdultAnti-HIV AgentsClinical Trials as TopicContraceptive Devices, FemaleFemaleHIV-1HIV InfectionsHumansMalawiMaleMiddle AgedPre-Exposure ProphylaxisPyrimidinesAnti-HIV AgentsDapivirinePyrimidinesVaginal Creams, Foams, and JelliesAdherenceClinical trialCouplesFemale controlled HIV preventionGenderGender relationsHIVMicrobicideQualitative researchSexual relationshipSub-Saharan AfricaVaginal ringWomen

Identifiers

PMID31111297
PMCPMC6864230
OpenAlexW2946081274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.