Evidence map›Paper›PMID 31111114›Full record

ArticleContemporary clinical trials communications2019

Preventing disability in older adults with mild cognitive impairment: A Strategy Training intervention study.

Juleen Rodakowski, Katlyn W Golias, Charles F Reynolds, Meryl A Butters, Oscar L Lopez, Mary Amanda Dew, Elizabeth R Skidmore

Open access · goldAbstract read
In one paragraph

Article in Contemporary clinical trials communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. A Need to Activate Lasting Engagement.The American journal of occupational therapy : official publication of the American Occupational Therapy Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Juleen RodakowskiDepartment of Occupational Therapy, University of Pittsburgh, USA.
Katlyn W GoliasDepartment of Occupational Therapy, University of Pittsburgh, USA.
Charles F ReynoldsDepartment of Psychiatry, University of Pittsburgh, USA.
Meryl A ButtersDepartment of Psychiatry, University of Pittsburgh, USA.
Oscar L LopezDepartment of Neurology, University of Pittsburgh, USA.
Mary Amanda DewClinical and Translational Science Institute, University of Pittsburgh, USA.
Elizabeth R SkidmoreDepartment of Occupational Therapy, University of Pittsburgh, USA.
University of Pittsburgh · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
TREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAMBOH, M. ILYAS · 1985 to 2019
$43.0M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Institutional Career Development CoreKL2TR001856 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, KRISTIN N, RUBIO, DORIS M · 2016 to 2025
$13.8M
RESEARCH METHODS COREP30MH090333 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REYNOLDS, CHARLES F. · 2011 to 2015
$8.3M
INFLUENCE OF STRATEGY TRAINING ON DISABILITY FOR OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENTR01AG056351 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RODAKOWSKI, JULEEN · 2019 to 2023
$3.2M
NCATS NIH HHS KL2 TR001856NCATS NIH HHS UL1 TR000005NIA NIH HHS P30 AG024827NIA NIH HHS P50 AG005133NIA NIH HHS R01 AG056351NIMH NIH HHS P30 MH090333
6 · The paper itself

Abstract

Non-pharmacological interventions designed to change cognitive function in older adults with Mild Cognitive Impairment have shown mixed results. Few studied interventions directly address preclinical disability. Slowing changes in disability are critical preserve independence and health related quality of life in older adults with Mild Cognitive Impairment. In this study, we discuss the design of the trial, challenges encountered, and solutions generated to guide future trials designed to prevent the onset of disability among at-risk older adults. We compared Strategy Training to enhanced-usual care in 30 older adults with Mild Cognitive Impairment. We recruited 79.7% (n = 188) of the potential participants through direct-to-consumer recruitment. We refined a three-step screening process, including a phone screen, initial in-person screening, and full in-person screening. This screening processes resulted in a high percentage of older adults completing the neuropsychological battery and adjudication of Mild Cognitive Impairment. Conducting a disability prevention among individuals without overt disability is a novel approach. Nevertheless, one of the greatest limitations to our project is the fact that follow-up is restricted to 1 year. Findings from this study can inform the design and conduct of future clinical trials that seek to slow progression of disability in older adults with Mild Cognitive Impairment.

Indexed as

Mild cognitive impairmentNon-pharmacological interventionsPre-clinical disabilityPrevention clinical trials

Identifiers

PMID31111114
PMCPMC6512744
OpenAlexW2942688064

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.