Evidence map›Paper›PMID 31111074›Full record

ArticleBioMed research international2019

Ferritin Genes Overexpression in PBMC and a Rise in Exercise Performance as an Adaptive Response to Ischaemic Preconditioning in Young Men.

Jan Mieszkowski, Magdalena Kochanowicz, Małgorzata Żychowska, Andrzej Kochanowicz, Agata Grzybkowska, Katarzyna Anczykowska, Piotr Sawicki, Andzelika Borkowska, Bartłomiej Niespodzinski, Jedrzej Antosiewicz

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07117643 (Influence of Remote Ischemic Preconditioning Reperfusion/Reocclusion Training and Physical Exercises on the Inflammatory, Angiogenic, Neurotrophic and Anti-tumor Potential of Human Serum in Vivio/in Vitro Studies - Role of Vitamin d and Iron Metabolism), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07117643 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Influence of Remote Ischemic Preconditioning Reperfusion/Reocclusion Training and Physical Exercises on the Inflammatory, Angiogenic, Neurotrophic and Anti-tumor Potential of Human Serum in Vivio/in Vitro Studies - Role of Vitamin d and Iron Metabolism

TypeinterventionalSponsorGdansk University of Physical Education and SportRan2025 to 2029Enrolled250ConditionsSport Medicine, Sport, Physiological Adaptations, Sport PerformanceArmsIschemic Preconditioning
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jan MieszkowskiGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Biochemistry, Gdansk, Poland.ORCID 0000-0001-6753-5139
Magdalena KochanowiczGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Biochemistry, Gdansk, Poland.
Małgorzata ŻychowskaGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Life Sciences, Gdansk, Poland.ORCID 0000-0002-9475-0448
Andrzej KochanowiczGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Gymnastics and Dance, Gdansk, Poland.
Agata GrzybkowskaGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Biochemistry, Gdansk, Poland.
Katarzyna AnczykowskaGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Biochemistry, Gdansk, Poland.
Piotr SawickiGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Gymnastics and Dance, Gdansk, Poland.
Andzelika BorkowskaMedical University of Gdansk, Department of Bioenergetics and Physiology of Exercise, Gdansk, Poland.
Bartłomiej NiespodzinskiKazimierz Wielki University in Bydgoszcz, Department of Anatomy and Biomechanics, Bydgoszcz, Poland.
Jedrzej AntosiewiczGdansk University of Physical Education and Sport, Faculty of Physical Education, Department of Biochemistry, Gdansk, Poland.ORCID 0000-0002-7871-6469
Gdansk University of Physical Education and Sport · PLGdańsk Medical University · PLKazimierz Wielki University in Bydgoszcz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe proposal of this study was to evaluate the effect of acute and ten-day ischaemic preconditioning (IPC) training procedure on the Wingate Anaerobic Test (WAnT), the ferritin H (

method34 healthy men volunteers (aged 20.7 ± 1.22 years) participated in the study. The effects of bilateral upper limb IPC and sham controlled condition were assessed in two experimental protocols: (a) the influence of acute (one time) IPC based on an experimental crossover study design and (b) the influence of ten-day IPC training treatment based on a random group assignment. At the beginning and at the end of each experiment upper body WAnT was performed and blood samples were collected to assess gene expression via quantitative PCR (qPCR).

resultsNo significant effect of one-time ischaemic preconditioning procedure was observed on upper body WAnT performance. Ten-day IPC training significantly increased upper limbs relative mean power (from 5.29 ± 0.50 to 5.79 ± 0.70 (W/kg), p < 0.05). One-time IPC caused significant decrease in

conclusionsOur findings suggest that ten-day IPC training intervention significantly affects upper limb relative peak power. The observed overexpression of FTH and FTL genes could be associated with adaptation response induced by prolonged IPC.

Indexed as

Gene Expression RegulationAdaptation, PhysiologicalAdolescentAdultAntigens, CDApoferritinsCross-Over StudiesExerciseFerritinsHumansIschemic PreconditioningLeukocytes, MononuclearMaleReceptors, TransferrinRNA, MessengerVolunteersAntigens, CDApoferritinsCD71 antigenFerritinsReceptors, TransferrinRNA, Messenger

Identifiers

PMID31111074
PMCPMC6487173
OpenAlexW2939307866

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.