Evidence map›Paper›PMID 31111051›Full record

ArticleBioMed research international2019

Infectivity of

Dongxiang Pan, Prasit Palittapongarnpim, Angkana Chaiprasert, Mei Lin, Dingwen Lin, Xi Long, Liwen Huang, Huifang Qin, Edward McNeil, Rushu Lan and 2 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Dongxiang PanSchool of Public Health, Guangxi Medical University, Nanning, Guangxi, 530021, China.
Prasit PalittapongarnpimDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok, 10700, Thailand.
Angkana ChaiprasertOffice of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.
Mei LinDepartment of Tuberculosis Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, Guangxi, 530021, China.
Dingwen LinDepartment of Tuberculosis Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, Guangxi, 530021, China.
Xi LongSchool of Public Health, Guangxi Medical University, Nanning, Guangxi, 530021, China.
Liwen HuangDepartment of Tuberculosis Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, Guangxi, 530021, China.
Huifang QinDepartment of Tuberculosis Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, Guangxi, 530021, China.
Edward McNeilEpidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, 90110, Thailand.ORCID 0000-0002-9492-1040
Rushu LanDepartment of Tuberculosis Prevention and Control, Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control, Nanning, Guangxi, 530021, China.ORCID 0000-0002-1176-9371
Xiaoqiang QiuSchool of Public Health, Guangxi Medical University, Nanning, Guangxi, 530021, China.ORCID 0000-0002-2442-4073
Virasakdi ChongsuvivatwongEpidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, 90110, Thailand.ORCID 0000-0002-9850-4463
Guangxi Center for Disease Prevention and Control · CNGuangxi Medical University · CNPrince of Songkla University · THNational Science and Technology Development Agency · THSiriraj Hospital · TH

Funding

TB/MDR-TB Research training and Capacity Strengthening for LMIC in Southeast Asia Phase II: Promotion of Diversity, Equity and Inclusion (DEI)D43TW009522 · FIC · PRINCE OF SONGKLA UNIVERSITY · PI Virasakdi Chongsuvivatwong · 2015 to 2026
$3.0M
FIC NIH HHS D43 TW009522
6 · The paper itself

Abstract

objectiveTo evaluate the infectivity of

methodsAdolescent school tuberculosis (TB) contact investigations were conducted for all reported index TB cases from November 2016 to December 2017 in Guangxi, China. Genotypes of index cases and contact cases were identified by 15-loci mycobacterial interspersed repetitive units-variable number tandem repeat and spoligotyping. Outcome variable was 5 levels' order of tuberculin skin test (TST) results to new active TB [0-5 mm, 6-9 mm, 10-14 mm, ≥ 15 mm (without TB), and ≥15 mm (with TB)]. Multivariate ordered logistic regression analysis was performed to evaluate the independent effect of genotypes of index case on contact screening outcome.

resultsBeijing genotype occurred more commonly in female index patients. One genotypic cluster of two index cases and one cluster of two contact cases were detected. The association between infectivity of Beijing genotype of index cases and outcome of contact investigation was statistically significant in univariate analysis but no so after adjustment for characteristics of contacts and sex of index cases (

conclusionThere was not enough evidence from our data to support that Beijing strains were more infective than non-Beijing strains in TB transmission in school setting.

Indexed as

GenotypeSchoolsAdolescentChinaEthnicityFemaleGenetic LociHumansLatent TuberculosisLogistic ModelsMaleMinisatellite RepeatsMultivariate AnalysisMycobacterium tuberculosisPhylogenyRegression Analysis

Identifiers

PMID31111051
PMCPMC6487147
OpenAlexW2937190140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.