Trial reportBioMed research international2019
Preoperative Management of MGD Alleviates the Aggravation of MGD and Dry Eye Induced by Cataract Surgery: A Prospective, Randomized Clinical Trial.
Trial report in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Effect of a single warm compress prior to ophthalmic surgery on ocular surface and intraoperative visibility: a randomised controlled study.BMJ open ophthalmology · 2023Trial
- New Therapeutic Strategy and Innovative Lubricating Ophthalmic Solution in Minimizing Dry Eye Disease Associated with Cataract Surgery: A Randomized, Prospective Study.Advances in therapy · 2020Trial
- Comparative Efficacy of Topical Eye-Drop Regimens for Dry Eye After Cataract Surgery: A Systematic Review and Network Meta-analysis.Ophthalmology and therapy · 2026Review
- Differential Characteristics, Mechanisms, and Clinical Strategies for Perioperative Dry Eye in Presenile Cataract and Age-Related Cataract.Healthcare (Basel, Switzerland) · 2026Review
- Pharmacological, Natural and Emerging Therapies for Meibomian Gland Dysfunction: A Review.Drugs · 2026Review
- A Practical Approach for Optimizing Ocular Surface Status Before Cataract Surgery to Improve Visual Outcomes and Reduce the Risk of Postoperative Dry Eye.Ophthalmology and therapy · 2025Review
- Unhappy 20/20: A New Challenge for Cataract Surgery.Journal of clinical medicine · 2025Article
- Association of Cataract History with Dry Eye Disease Signs and Symptoms in the DREAM Study.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- The impact of cataract surgery on tear film physiology: signs and symptoms, progression and treatment.Frontiers in medicine · 2025Review
- Comparison of two treatments for dry eye disease after corneal refractive surgery.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2025Article
- SMILE and ICL implantation on the ocular surface and meibomian glands in patients with postoperative myopia.BMC ophthalmology · 2024Article
- Meibomian Gland Dysfunction Clinical Practice Guidelines.Japanese journal of ophthalmology · 2023Article
- Cataract surgery in ocular surface disease.Indian journal of ophthalmology · 2023Review
- The Effect of Meibomian Gland Dysfunction on Laser-Assisted In Situ Keratomileusis in Asymptomatic Patients.Ophthalmology and therapy · 2023Article
- Analysis of postoperative ocular surface changes and intervention effect after pars plana vitrectomy in meibomian gland dysfunction dry eye patients.International journal of ophthalmology · 2023Article
- Perioperative nuances of cataract surgery in ocular surface disorders.Indian journal of ophthalmology · 2022Review
- Prevalence and Characteristics of Dry Eye Disease After Cataract Surgery: A Systematic Review and Meta-Analysis.Ophthalmology and therapy · 2022Review
- The Effect of Past Cataract Surgery within the Medium to Long-Term Period on Patients with Dry Eye Disease.Journal of clinical medicine · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the effect of preoperative treatment and postoperative enhanced anti-inflammatory treatment on alleviating meibomian gland dysfunction (MGD) and dry eye induced by cataract surgery.
designProspective, randomized clinical trial.
methodsA total of 120 cataract patients with moderate obstructive-MGD were enrolled and randomized with 60:30:30 number of patients in cohorts I, II, and III, respectively: Cohort I: routine postoperative anti-inflammatory treatment; Cohort II: preoperative treatment (warming compress, lid hygiene, and anti-inflammatory treatment) and routine postoperative anti-inflammatory treatment; Cohort III: enhanced postoperative anti-inflammatory treatment. MAIN OUTCOMES MEASURES: All participants were examined preoperatively and postoperatively for ocular symptom score (OSS), noninvasive keratographic tear break-up time (NIKBUT), corneal fluorescein staining, Schirmer I test, lid margin, meibum quality and expressibility, and meibomian gland dropout.
resultsOcular surface disorders and MGD showed aggravated status at 1 month postoperatively in Cohort I and Cohort III, and the aggravated MGD resolved by 3 months postoperatively. At 1 month postoperatively, Cohort II and Cohort III presented high NIKBUT and low OSS, lid margin, and meibum quality and expressibility (Cohort II vs Cohort I: all
conclusionPreoperative management of MGD is effective and optimal in alleviating obstructive-MGD and dry eye induced by cataract surgery.
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Registered trials
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