ArticleIranian journal of public health2019
Clinical Significance of Detection of Coagulation Indexes, Immune Factors and Inflammatory Factors in Patients with Pregnancy-Induced Hypertension Syndrome in China.
Article in Iranian journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Late-pregnancy air pollution exposure and neonatal anthropometry with and without gestational hypertension.iScience · 2026Article
- COVID-19 disease: novel clinical manifestations and therapeutic exploration.Archives of medical science : AMS · 2026Article
- Article
- Low-molecular-weight heparins utilization in pregnant and postpartum women: a real-world analysis in China (2016-2021).Frontiers in pharmacology · 2025Article
- Role of coagulation indices in assessinghypertensive disorders in pregnancy and predicting delivery outcomes.American journal of translational research · 2024Article
- Coagulation parameters correlate to venous thromboembolism occurrence during the perioperative period in patients with spinal fractures.Journal of orthopaedic surgery and research · 2023Article
- Predictive value of coagulation function and D-dimer for pregnancy outcome in pregnancy-induced hypertension.American journal of translational research · 2023Article
- Exploring the role of T helper subgroups and their cytokines in the development of pregnancy-induced hypertension.Frontiers in immunology · 2023Article
- Analysis of alterations of serum inflammatory cytokines and fibrosis makers in patients with essential hypertension and left ventricular hypertrophy and the risk factors.American journal of translational research · 2022Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the clinical significance of monitoring the coagulation indexes, immune factors and inflammatory factors in pregnancy-induced hypertension syndrome (PIH).
methods90 pregnant women with PIH admitted in Weihaiwei People's Hospital of Shandong Province, China from 2016 to 2017 were collected, including 45 cases in mild-moderate group and 45 cases in severe group. Another 45 normal pregnant women at the same period were selected as control group. The immune indexes, four index signs of coagulation bloods and serum inflammatory factors in three groups of subjects were determined.
resultsThe levels of complement 3 (C3), complement 4 (C4), immunoglobulin A (IgA), immunoglobulin G (IgG) and immunoglobulin M (IgM) were successively increased in severe PIH group, mild-moderate PIH group and normal pregnancy group (
conclusionPregnant women with PIH are in a hypercoagulable state and have a higher risk of thrombus and secondary hyperfibrinolysis. Immune factors and inflammatory factors are also associated with the occurrence and development of the disease. Monitoring the changes in coagulation indexes and levels of immune factors and inflammatory factors provide an important reference value for clinical treatment and prevention of complications.
Indexed as
Identifiers
31110978PMC6500546W2946474473What OpenQuestion holds
Registered trials
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