ReviewPediatric gastroenterology, hepatology & nutrition2019
Functional Gastrointestinal Disorders in Infancy: Impact on the Health of the Infant and Family.
Review in Pediatric gastroenterology, hepatology & nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06268964 (Comparative Effect of Trimebutine and Probiotics on Functional Abdominal Pain Disorders), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effect of Trimebutine and Probiotics on Functional Abdominal Pain Disorders (FAPD) in Children: Randomized Clinical Trial (RCT)
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.
- Faecal Microbiota in Infants and Young Children with Functional Gastrointestinal Disorders: A Systematic Review.Nutrients · 2022Pooled it
- Gastrointestinal Tolerance of an Infant Formula Manufactured from Extensively Hydrolysed Protein in Healthy Term Infants.Nutrients · 2023Trial
- The use of two Comfort Young Child Formulas in the dietary management of toddlers with functional constipation: a randomized controlled trial.BMC pediatrics · 2022Trial
- Wangshi Baochi Pill for functional dyspepsia syndrome in infants and toddlers: a multicenter randomized placebo-controlled trial.Translational pediatrics · 2026Article
- Review
- Review
- Complementary Feeding Frequency and Maternal Health: Reducing Anxiety and Improving Sleep Through Biobehavioral Pathways.Nature and science of sleep · 2026Article
- Cesarean section and socioeconomic status are associated with Bifidobacterium abundance and intestinal physiology: observations from a cross-sectional study in formula-fed infants.BMC microbiology · 2025Article
- Sustainable Fluoride Determination in Selected Infant Juices Available on the Serbian Market: Health Risk Assessment.Biological trace element research · 2025Article
- Breaking the cycle: Psychological and social dimensions of pediatric functional gastrointestinal disorders.World journal of clinical pediatrics · 2025Article
- Gut Microbiota Profile and Functional Gastrointestinal Disorders in Infants: A Longitudinal Study.Nutrients · 2025Article
- Functional gastrointestinal disorders predictors in neonates and toddlers: A machine learning approach to risk assessment.Heliyon · 2025Article
- Approach to the spectrum of infant non-IgE-mediated food allergy manifestations and physiologic infant behaviors.Current problems in pediatric and adolescent health care · 2025Review
- Serum eosinophil-derived neurotoxin: a new promising biomarker for cow's milk allergy diagnosis.Pediatric research · 2024Article
- Perceived Infant Discomfort Linked to Lower Maternal Oral Health Quality of Life: Results from a Cross-Sectional Study.Journal of clinical medicine · 2024Article
- South Korean first-time mothers' knowledge of digestive health problems in infancy and their utilization of health care facilities for digestive health concerns: a descriptive study.Child health nursing research · 2024Article
- Infantile Colic: A Survey of Physicians in Pakistan.Pediatric gastroenterology, hepatology & nutrition · 2024Article
- Growth and gut comfort of healthy term infants exclusively fed with a partially hydrolysed protein-based infant formula: a randomized controlled double-blind trial.Frontiers in pediatrics · 2024Article
- Investigation of the gastric digestion behavior of commercial infant formulae using anFrontiers in nutrition · 2024Article
- A cross-sectional study on stool- and gastrointestinal-related outcomes of Mexican infants consuming different formulae.BMC pediatrics · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional gastrointestinal disorders (FGIDs) such as infantile colic, constipation and colic occur in almost half of the infants. The aim of this paper is to provide a critical and updated review on the management of FGIDs and their impact on the health of the infant and family to health care physicians. Guidelines and expert recommendations were reviewed. FGIDs are a frequent cause of parental concern, impairment in quality of life of infants and relatives, and impose a financial burden to families, health care, and insurance. Therefore, primary management of the FGIDs should be focused on improving the infants' symptoms and quality of life of the family. If more than parental reassurance is needed, available evidence recommends nutritional advice as it is an effective strategy and most of the time devoid of adverse effects. The role of healthcare providers in reassuring parents and proposing the correct behavior and nutritional intervention by avoiding inappropriate use of medication, is essential in the management of FGIDs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.