Evidence map›Paper›PMID 31110896›Full record

ReviewJournal of pediatric intensive care2016

Perpetual and Virtual Patients for Cardiorespiratory Physiological Studies.

David Brossier, Michael Sauthier, Xavier Alacoque, Benoit Masse, Redha Eltaani, Bernard Guillois, Philippe Jouvet

Abstract readReview
In one paragraph

Review in Journal of pediatric intensive care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David BrossierPediatric Intensive Care Unit, Sainte Justine University Health Centre, Montreal, Quebec, Canada.
Michael SauthierPediatric Intensive Care Unit, Sainte Justine University Health Centre, Montreal, Quebec, Canada.
Xavier AlacoqueDepartment of Anesthesia, Perioperative and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Benoit MasseSainte-Justine UHC Research Institute, Sainte Justine University Hospital, Montreal, Canada.
Redha EltaaniSainte-Justine UHC Research Institute, Sainte Justine University Hospital, Montreal, Canada.
Bernard GuilloisDepartment of Neonatology, University Hospital of Caen, Caen, France.
Philippe JouvetPediatric Intensive Care Unit, Sainte Justine University Health Centre, Montreal, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a result of innovations in informatics over the last decades, physiologic models elaborated in the second half of the 20th century could be transformed into specific virtual patients called computational models. These models, developed initially for teaching purposes, are of great potential interest in responding to current concerns about improving patient care and safety. However, even if there are obvious advantages to using computational models in cardiorespiratory management, major concerns persist as to their reliability and their ability to recreate real patient physiologic evolution over time. Once developed, these models require complex validation and configuration phases prior to implementation in daily practice. This article focuses on the development of computational models, and reviews the methodologies to clinically validate the models including specific patient databases (perpetual patients) and the use in clinical practice including very high fidelity simulation.

Indexed as

cardiorespiratory physiologychildrendatabasesintensive caremodelingsimulation

Identifiers

PMID31110896
PMCPMC6512414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.