Evidence map›Paper›PMID 31110828›Full record

ArticleCase reports in hematology2019

Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations.

Benedetta Mariotti, Federico Meconi, Raffaele Palmieri, Eleonora De Bellis, Serena Lavorgna, Tiziana Ottone, Vincenza Martini, Francesco Lo-Coco, Laura Cicconi

Abstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. NPM1 Mutated, BCR-ABL1 Positive Myeloid Neoplasms: Review of the Literature.Mediterranean journal of hematology and infectious diseases · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Benedetta MariottiDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.ORCID 0000-0001-8999-4547
Federico MeconiDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.ORCID 0000-0003-4369-3321
Raffaele PalmieriDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Eleonora De BellisDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Serena LavorgnaDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Tiziana OttoneDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Vincenza MartiniUOC Ematologia, Ospedale "Fabrizio Spaziani", Frosinone, Italy.
Francesco Lo-CocoDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.
Laura CicconiDepartment of Biomedicine and Prevention, University Tor Vergata, Rome, Italy.ORCID 0000-0001-5642-3051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case report of a patient with acute myeloid leukemia (AML) characterized by the simultaneous presence of nucleophosmin 1 (NPM1) mutation and the breakpoint cluster region-Abelson (BCR-ABL) fusion oncogene. Our findings emphasize the importance of routinely including BCR-ABL in the diagnostic workup of AML in order to offer to the patients the most appropriate risk category and treatment options.

Identifiers

PMID31110828
PMCPMC6487162

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.