Evidence map›Paper›PMID 31110709›Full record

ArticleClinical case reports2019

A hypercoagulable state leading to venous limb gangrene associated with occult lung adenocarcinoma.

Matthew M A Waite, Anthony W Martinelli, Stephen D Preston, Emma Gudgin, Emily Symington, Robert C Rintoul, Adam Peryt, Patrick Coughlin, Paul Hayes, David Gilligan and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Matthew M A WaiteAddenbrooke's Hospital University of Cambridge School of Clinical Medicine Cambridge UK.ORCID 0000-0002-6528-5022
Anthony W MartinelliDepartment of Thoracic Oncology Papworth Hospital NHS Foundation Trust Cambridge UK.
Stephen D PrestonDepartment of Thoracic Oncology Papworth Hospital NHS Foundation Trust Cambridge UK.ORCID 0000-0002-6836-3591
Emma GudginDepartment of Haematology Papworth Hospital NHS Foundation Trust Cambridge UK.
Emily SymingtonDepartment of Haematology Papworth Hospital NHS Foundation Trust Cambridge UK.
Robert C RintoulDepartment of Thoracic Oncology Papworth Hospital NHS Foundation Trust Cambridge UK.
Adam PerytDepartment of Thoracic Surgery Papworth Hospital NHS Foundation Trust Cambridge UK.
Patrick CoughlinDepartment of Vascular and Endovascular Surgery Addenbrooke's Hospital Cambridge UK.
Paul HayesDepartment of Vascular and Endovascular Surgery Addenbrooke's Hospital Cambridge UK.
David GilliganDepartment of Thoracic Oncology Papworth Hospital NHS Foundation Trust Cambridge UK.
Martin BesserDepartment of Haematology Papworth Hospital NHS Foundation Trust Cambridge UK.
Papworth Hospital NHS Foundation Trust · GBAddenbrooke's Hospital · GBUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of lung adenocarcinoma-associated hypercoagulability leading to venous limb gangrene, managed successfully with argatroban and then dabigatran. Use of idarucizumab permitted diagnostic investigations, leading to targeted antineoplastic therapy with crizotinib, surgical resection with curative intent, and continued survival over 2 years after the index event.

Indexed as

argatrobandabigatranhematologyhypercoagulabilitylung adenocarcinomarespiratory

Identifiers

PMID31110709
PMCPMC6510014
OpenAlexW2944286670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.