Cerebellar Cryptococcal Abscess in HIV-Negative Patient: A Case Report and Literature Review.

Ni Putu Sriwidyani, Ni Luh G Sagita Dewi, I Nyoman Golden, I Putu Eka Widyadharma

Open access · diamondAbstract readCase Reports

In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.5field-weighted citation impact, top 33% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Case reports in hepatology · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ni Putu SriwidyaniAnatomical Pathology Department, Faculty of Medicine Udayana University, Sanglah General Hospital, Bali, Indonesia.

Ni Luh G Sagita DewiAnatomical Pathology Department, Faculty of Medicine Udayana University, Sanglah General Hospital, Bali, Indonesia.

I Nyoman GoldenNeurosurgery Department, Faculty of Medicine Udayana University, Sanglah General Hospital, Bali, Indonesia.

I Putu Eka WidyadharmaNeurology Department, Faculty of Medicine Udayana University, Sanglah General Hospital, Bali, Indonesia.

Udayana University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCryptococcus is a common cause of opportunistic infection in HIV-positive patients. While the incidence of this disease has decreased in AIDS-associated cases, cryptococcal infection in immune-competent person has been increased. CASE PRESENTATION: We report a case of cryptococcosis and literature review of pathogenesis and clinical aspects of cryptococcal central nervous system infection. A 64-year-old man, from Flores, complaining of severe headache since a few days before admitted to hospital. Head MRI showed multiple hypointense lesions in the left cerebellar hemisphere, suspected abscess or metastatic process. HIV testing was non-reactive. Surgery was performed, and microscopic evaluation revealed multiple abscesses containing PAS-positive budding yeasts consistent with cryptococcal abscesses.

conclusionCryptococcosis rarely occur in immunocompetent patients. The clinical manifestation depends on pathogenic factors of pathogen and host factor. Treatment is with the administration of antifungal drugs, and the prognosis mostly depends on the underlying disease.

Indexed as

AbscessCerebellumCryptococcosisFungalImmune-competent

Identifiers

PMID31110584

DOI10.3889/oamjms.2019.320

PMCPMC6514353

OpenAlexW2944806326

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.