Evidence map›Paper›PMID 31110539›Full record

ArticleArchives of medical science : AMS2019

Diagnostic effectiveness of soluble triggering receptor expressed on myeloid cells-1 in sepsis, severe sepsis and septic shock.

Monika Jedynak, Andrzej Siemiatkowski, Robert Milewski, Barbara Mroczko, Maciej Szmitkowski

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Sepsis Prediction: Biomarkers Combined in a Bayesian Approach.International journal of molecular sciences · 2025
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  3. Article
  4. Review
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  10. Review
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  12. Article
  13. Biomarkers of sepsis: time for a reappraisal.Critical care (London, England) · 2020
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Monika JedynakDepartment of Anaesthesiology and Intensive Therapy, Medical University of Bialystok, Bialystok, Poland.
Andrzej SiemiatkowskiDepartment of Anaesthesiology and Intensive Therapy, Medical University of Bialystok, Bialystok, Poland.
Robert MilewskiDepartment of Anaesthesiology and Intensive Therapy, Medical University of Bialystok, Bialystok, Poland.
Barbara MroczkoDepartment of Anaesthesiology and Intensive Therapy, Medical University of Bialystok, Bialystok, Poland.
Maciej SzmitkowskiDepartment of Anaesthesiology and Intensive Therapy, Medical University of Bialystok, Bialystok, Poland.
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSensitivities and specificities of clinical signs and biochemical tests in sepsis diagnosis are not satisfactory. The aim of the study was to assess the diagnostic usefulness of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in sepsis, severe sepsis and septic shock against interleukin-6 (IL-6), C-reactive protein (CRP) and procalcitonin (PCT). MATERIAL AND

methodsA prospective, observational study was conducted in 85 adults with sepsis, severe sepsis or septic shock and 22 with non-infective systemic inflammatory response syndrome (NI-SIRS). Serum levels of sTREM-1, CRP, PCT and IL-6 were measured on admission.

resultsMedian serum sTREM-1 concentrations were higher in severe sepsis (540 pg/ml) and septic shock (536 pg/ml) in comparison with NI-SIRS patients (

conclusionsSerum level of sTREM-1 has lower effectiveness as a diagnostic biomarker in severe sepsis and septic shock, in comparison with CRP and IL-6.

Indexed as

diagnosisinfectioninflammationmediators

Identifiers

PMID31110539
PMCPMC6524181
OpenAlexW2917692603

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.