Evidence map›Paper›PMID 31110496›Full record

ArticleFrontiers in microbiology2019

Potential Role of Biofilm Formation in the Development of Digestive Tract Cancer With Special Reference to

Cosmeri Rizzato, Javier Torres, Elena Kasamatsu, Margarita Camorlinga-Ponce, Maria Mercedes Bravo, Federico Canzian, Ikuko Kato

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
  2. Review
  3. Characterization ofFrontiers in microbiology · 2026
    Article
  4. From gut to mouth: salivary signatures of carcinogenic microbiota.Frontiers in cellular and infection microbiology · 2026
    Review
  5. Review
  6. Article
  7. Biofilm-producing and carbapenems-resistant Escherichia coli nosocomial uropathogens: a cross-sectional study.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  8. Molecular Mechanisms of Biofilm Formation inAntibiotics (Basel, Switzerland) · 2024
    Review
  9. Optimization ofInternational journal of molecular sciences · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. The Role ofMicroorganisms · 2023
    Review
  15. Article
  16. Article
  17. Titanium complexes affectRSC medicinal chemistry · 2023
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 6 countries.

Cosmeri RizzatoDepartment of Translation Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Javier TorresUnidad de Investigación en Enfermedades Infecciosas, Unidades Médicas de Alta Especialidad Pediatría, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Elena KasamatsuInstituto de Investigaciones en Ciencias de la Salud, National University of Asunción, Asunción, Paraguay.
Margarita Camorlinga-PonceUnidad de Investigación en Enfermedades Infecciosas, Unidades Médicas de Alta Especialidad Pediatría, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Maria Mercedes BravoGrupo de Investigación en Biología del Cáncer, Instituto Nacional de Cancerología, Bogotá, Colombia.
Federico CanzianGenomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ikuko KatoDepartment of Oncology and Pathology, Wayne State University School of Medicine, Detroit, MI, United States.
Mexican Social Security Institute · MXGerman Cancer Research Center · DEInstituto Nacional de Cancerología · COUniversidad Nacional de Asunción · PYUniversity of Pisa · ITWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria are highly social organisms that communicate via signaling molecules and can assume a multicellular lifestyle to build biofilm communities. Until recently, complications from biofilm-associated infection have been primarily ascribed to increased bacterial resistance to antibiotics and host immune evasion, leading to persistent infection. In this theory and hypothesis article we present a relatively new argument that biofilm formation has potential etiological role in the development of digestive tract cancer. First, we summarize recent new findings suggesting the potential link between bacterial biofilm and various types of cancer to build the foundation of our hypothesis. To date, evidence has been particularly convincing for colorectal cancer and its precursor, i.e., polyps, pointing to several key individual bacterial species, such as

Indexed as

biofilmcancerHelicobacter pyloripersistent infectionvirulence

Identifiers

PMID31110496
PMCPMC6501431
OpenAlexW2943798430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.