ArticleJournal of oral and maxillofacial pathology : JOMFP
A retrospective study of clinicopathological features of oral squamous cell carcinoma with and without oral submucous fibrosis.
Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Distinctive tumor biology of oral squamous cell carcinoma associated with oral submucous fibrosis and its suppressive immune microenvironment.BMC oral health · 2025Article
- Article
- Correlation of clinical presentation with prognosis in oral squamous cell carcinoma associated with oral submucous fibrosis.BMC cancer · 2025Article
- Assessment and Correlation of TP53 With Histological Parameters of Oral Squamous Cell Carcinoma.Cureus · 2024Article
- Comprehensive analysis of clinicopathological characteristics in oral squamous cell carcinoma arising from oral submucous fibrosis: a retrospective study.Discover oncology · 2024Article
- Article
- Role of Physiotherapy in HPV Proven Cases of Oral Submucous Fibrosis.Journal of pharmacy & bioallied sciences · 2023Review
- Role of coronoidectomy and temporalis myotomy in surgical management of oral submucous fibrosis.Oral and maxillofacial surgery · 2022Article
- Prevalence of oral submucous fibrosis in patients visiting dental OPD of a dental college in Kanpur: A demographic study.Journal of family medicine and primary care · 2019Article
- Article
- Prevalence of Human Papillomavirus (HPV) 16 and 18 in Oral Malignant and Potentially Malignant Disorders: A Polymerase Chain Reaction Analysis - A Comparative Study.Annals of maxillofacial surgeryArticle
- PTEN and α-SMA Expression and Diagnostic Role in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma with Concomitant Oral Submucous Fibrosis.Journal of oral & maxillofacial researchArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextOral submucous fibrosis (OSF) is strongly associated with areca nut usage; the existence of OSF in patients with oral squamous cell carcinoma (OSCC) is an indicator of areca nut-induced carcinogenesis. As areca nut follows a discrete molecular path for oral carcinogenesis, this could be the basis why OSCC patients with OSF are different and are currently projected to constitute a distinct clinicopathologic entity.
aimThis study aims to analyze and compare the demographics, risk factors and clinicopathologic features of OSCC patients with and without OSF. MATERIALS AND
methodsA retrospective review of OSCC cases treated in the institution from 2008 to 2013 was done. Sixty OSCC of buccal mucosa were selected, of which 30 were with concomitant OSF and 30 without OSF. Demographics, risk factors and clinicopathological features were studied. The data were analyzed by SPSS-20 software, using the Pearson Chi-square, Fisher's exact and Mann-Whitney U-tests.
resultsOSCC cases with OSF were younger (mean age 40.5 vs. 54 years) compared to those without OSF (
conclusionAlthough majority of OSCC patients with OSF were young with a better grade of tumor differentiation, other clinicopathologic features having prognostic significance did not differ significantly between the two groups. Therefore, OSCC arising in background OSF as a distinct entity is uncertain.
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