Evidence map›Paper›PMID 31110439›Full record

ArticleJournal of oral and maxillofacial pathology : JOMFP

Association of matrix metalloproteinase 2 and matrix metalloproteinase 9 gene polymorphism in aggressive and nonaggressive odontogenic lesions: A pilot study.

Devu Aloka, S K Padmakumar, Sanish Sathyan, Maria Sebastian, Moinak Banerjee, V T Beena

Abstract read
In one paragraph

Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Molecular biological findings of ameloblastoma.The Japanese dental science review · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Devu AlokaDepartment of Oral Pathology and Microbiology, Government Dental College, Thiruvananthapuram, Kerala, India.
S K PadmakumarDepartment of Oral Pathology and Microbiology, Government Dental College, Thiruvananthapuram, Kerala, India.
Sanish SathyanHuman Molecular Genetics Laboratory, Rajiv Gandhi Institute of Biotechnology, Thiruvananthapuram, Kerala, India.
Maria SebastianHuman Molecular Genetics Laboratory, Rajiv Gandhi Institute of Biotechnology, Thiruvananthapuram, Kerala, India.
Moinak BanerjeeHuman Molecular Genetics Laboratory, Rajiv Gandhi Institute of Biotechnology, Thiruvananthapuram, Kerala, India.
V T BeenaDepartment of Oral Pathology and Microbiology, Government Dental College, Kottayam, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThe exact factors that determine the biological behavior of odontogenic lesions have not been thoroughly established yet. The influence of the matrix metalloproteinases (MMPs) on the clinical behavior of these lesions was recently brought to light.

aimsWe did a pioneer study to investigate the association of SETTINGS AND

designA case-control study conducted in the Department of Oral Pathology and Microbiology, Government Dental College, Trivandrum and Human Molecular Genetics Laboratory, Rajiv Gandhi Institute of Biotechnology and Poojappura, Trivandrum, Kerala. SUBJECTS AND

methodsDNA from the blood samples of histopathologically proven ameloblastoma ( STATISTICAL ANALYSIS USED: Chi-square analysis was done to assess the association of gene polymorphisms among the cases and controls.

resultsAmeloblastomas showed a higher frequency of mutant allele (T = 0.43;

conclusions

Indexed as

Ameloblastomamatrix metalloproteinaseodontogenicpromotersingle-nucleotide polymorphism

Identifiers

PMID31110439
PMCPMC6503786

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.