Evidence map›Paper›PMID 31110403›Full record

ArticleJournal of orthopaedics

The attempt of spontaneous repair of rotator cuff tear: The role of periostin.

Stefano Gumina, Martina Leopizzi, Michele Carnovale, Natale Porta, Giuseppe Giannicola, Ciro Villani, Vittorio Candela

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stefano GuminaDept. of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Istituto Clinico Ortopedico Traumatologico (ICOT), Latina, Italy.
Martina LeopizziDept of Anatomy and Histology, Sapienza University of Rome, Italy.
Michele CarnovaleDept. of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Natale PortaDept of Anatomy and Histology, Sapienza University of Rome, Italy.
Giuseppe GiannicolaDept. of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Ciro VillaniDept. of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Vittorio CandelaDept. of Anatomical, Histological, Forensic Medicine and Orthopaedics Sciences, Sapienza University of Rome, Istituto Clinico Ortopedico Traumatologico (ICOT), Latina, Italy.
Sapienza University of Rome · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of a periostin-rich microenvironment in areas associated with insult, orchestrating pathways of repair and rebuilding, is documented. Literature lacks information regarding the presence of periostin in the context of rotator cuff tear (RCT). 55 consecutive patients with RCT were enrolled. Immunohistochemical periostin detection was performed on tissue samples excised from tear margins. Our study documented the presence of periostin in the margins of RCT. It is plausible that, when a tear occurs, multiple stimuli, both mechanical and inflammatory, lead to the development of a periostin-rich microenvironment as an attempt to tendon healing.

Indexed as

Periostin propertiesPeriostin synthesisRotator cuff tear healingShoulder tendon diseaseTendon healing

Identifiers

PMID31110403
PMCPMC6512582
OpenAlexW2943646342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.