ArticleScientific reports2019
FABP1 controls hepatic transport and biotransformation of Δ
Open access · goldAbstract read
In one paragraph
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Fatty Acid-Binding Proteins and Substance Use Disorders: From Lipid Signaling to Therapeutic Targets.Genes · 2026Review
- Integrative network analysis reveals organizational principles of the endocannabinoid system.Journal of cannabis research · 2026Article
- Characterization of the Formation of the Acyl Glucuronide Metabolite of 7-Carboxy-Cannabidiol in Human Liver, Kidney, and Intestinal Microsomes andACS medicinal chemistry letters · 2026Article
- Population pharmacokinetic modelling revealed large variability in oromucosal absorption of ΔBritish journal of clinical pharmacology · 2026Article
- Perinatal omega-3 sex-selectively mitigates neuropsychiatric impacts of prenatal THC in the cortico-striatal-hippocampal circuit.Molecular psychiatry · 2025Article
- Chronic administration of a cannabis-derived mixture at an antihyperalgesic dose does not significantly enhance hepatotoxicity or the development of metabolic dysfunction-associated steatohepatitis in male mice.Experimental biology and medicine (Maywood, N.J.) · 2025Article
- Influences of metabolism and lipid homeostasis on regulatory vs. conventional T cells and implications for autoimmunity.Frontiers in immunology · 2025Review
- CYP2C9, CYP3A and CYP2C19 metabolize Δ9-tetrahydrocannabinol to multiple metabolites but metabolism is affected by human liver fatty acid binding protein (FABP1).Biochemical pharmacology · 2024Article
- Application of Monoclonal Antibodies against Naturally Occurring Bioactive Ingredients.Antibodies (Basel, Switzerland) · 2024Review
- Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism.Molecular pharmacology · 2024Article
- Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism.bioRxiv : the preprint server for biology · 2024Article
- Fatty acid binding protein 7 plays an important modulatory sex-dependent role on brain endocannabinoid levels and THC metabolism.PloS one · 2024Article
- Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years.Pharmacological reviews · 2023Review
- The Multifunctional Family of Mammalian Fatty Acid-Binding Proteins.Annual review of nutrition · 2023Review
- Impact of Intracellular Lipid Binding Proteins on Endogenous and Xenobiotic Ligand Metabolism and Disposition.Drug metabolism and disposition: the biological fate of chemicals · 2023Review
- Deciphering Complex Interactions in Bioactive Lipid Signaling.Molecules (Basel, Switzerland) · 2023Article
- Fatty acid binding protein 5 regulates docetaxel sensitivity in taxane-resistant prostate cancer cells.PloS one · 2023Article
- Pharmacokinetics of Cannabis and Its Derivatives in Animals and Humans During Pregnancy and Breastfeeding.Frontiers in pharmacology · 2022Review
- In Utero Exposure to Δ9-Tetrahydrocannabinol Leads to Postnatal Catch-Up Growth and Dysmetabolism in the Adult Rat Liver.International journal of molecular sciences · 2021Article
- Overview of Cannabis including Kampo Medicine and Therapy for Treatment of Dementia: A Review.Frontiers in pharmacology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Matthew W ElmesDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA. matthew.elmes@stonybrook.edu.
Lauren E PrentisDepartment of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, 11794, USA.
Luke L McGoldrickDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Christopher J GiulianoDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Joseph M SweeneyDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Olivia M JosephDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Joyce CheDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Gregory S CarbonettiDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Keith StudholmeDepartment of Anesthesiology, Stony Brook University, Stony Brook, New York, 11794, USA.ORCID http://orcid.org/0000-0002-0037-514X
Dale G DeutschDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Robert C RizzoDepartment of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, 11794, USA.
Steven E GlynnDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA.
Martin KaczochaDepartment of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, 11794, USA. martin.kaczocha@stonybrook.edu.
Stony Brook University · USStony Brook Medicine · US
Funding
X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6MAnandamide Transport InhibitorsR01DA035923 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI KACZOCHA, MARTIN · 2013 to 2017
$3.8MDevelopment, Validation, and Application of Structure-based Tools for Computational Molecular DesignR35GM126906 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI ROBERT C. RIZZO · 2018 to 2026
$3.2MFABPs: Novel Roles in Pain and InflammationR01DA035949 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI KACZOCHA, MARTIN · 2014 to 2022
$3.0MChemical Biology Training InterfaceT32GM136572 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI ELIZABETH M BOON, Jessica Chuang Seeliger · 2020 to 2026
$2.9MAcquisition of an Applied Biosystems 4000 QTRAP Mass SpectrometerS10RR023680 · NCRR · STATE UNIVERSITY NEW YORK STONY BROOK · PI IDEN, CHARLES R · 2007 to 2007
$435kRegulation of Cannabinoid Metabolism by Hepatic FABPsF31DA042545 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI ELMES, MATTHEW WILLIAM · 2016 to 2017
$67kNCRR NIH HHS S10 RR023680NIDA NIH HHS F31 DA042545NIDA NIH HHS R01 DA035923NIDA NIH HHS R01 DA035949NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R35 GM126906NIGMS NIH HHS T32 GM136572
Abstract
The increasing use of medical marijuana highlights the importance of developing a better understanding of cannabinoid metabolism. Phytocannabinoids, including ∆
Indexed as
AnimalsBinding SitesBiotransformationCells, CulturedCrystallography, X-RayDronabinolFatty Acid-Binding ProteinsFemaleHepatocytesLiverMaleMice, Inbred C57BLModels, MolecularDronabinolFABP1 protein, humanFabp1 protein, mouseFatty Acid-Binding Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.