ArticleNature chemistry2019
A catalytically active [Mn]-hydrogenase incorporating a non-native metal cofactor.
Article in Nature chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 66 citations in OpenAlex.
- Reprogramming NAD(P)Angewandte Chemie (International ed. in English) · 2026Article
- Eco-Nanozymology: A Catalytic Paradigm Integrating Energy, Environment, and Ecology.Nano-micro letters · 2026Review
- Variations in the Coordination Sphere of Ruthenacyclic Carbamoyl Complexes: Mapping Their Suitability for Direct Conjugation.ACS omega · 2025Article
- From [2Mn2S] Diamond Cores to Butterfly Rhombs: Transformations That Highlight Alternating Peptide Binding Sites.Inorganic chemistry · 2024Article
- Artificial Small Molecules as Cofactors and Biomacromolecular Building Blocks in Synthetic Biology: Design, Synthesis, Applications, and Challenges.Molecules (Basel, Switzerland) · 2023Review
- A versatile artificial metalloenzyme scaffold enabling direct bioelectrocatalysis in solution.Science advances · 2022Article
- Structure, reactivity and catalytic properties of manganese-hydride amidate complexes.Nature chemistry · 2022Article
- Functionalised Cofactor Mimics for Interactome Discovery and Beyond.Angewandte Chemie (International ed. in English) · 2022Review
- Mononuclear manganese complexes as hydrogen evolving catalysts.Frontiers in chemistry · 2022Article
- Diversifying Metal-Ligand Cooperative Catalysis in Semi-Synthetic [Mn]-Hydrogenases.Angewandte Chemie (International ed. in English) · 2021Article
- Transfer hydrogenation catalysis in cells.RSC chemical biology · 2021Review
- Heterologous Hydrogenase Overproduction Systems for Biotechnology-An Overview.International journal of molecular sciences · 2020Review
- Artificial Metalloenzymes: From Selective Chemical Transformations to Biochemical Applications.Molecules (Basel, Switzerland) · 2020Review
- Methanogenesis involves direct hydride transfer from HNature reviews. Chemistry · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Nature carefully selects specific metal ions for incorporation into the enzymes that catalyse the chemical reactions necessary for life. Hydrogenases, enzymes that activate molecular H
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.