ArticleScientific reports2019
Early Social Stress Promotes Inflammation and Disease Risk in Rhesus Monkeys.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Adaptive immune responses to vaccination reflect social status at first exposure in female rhesus macaques.bioRxiv : the preprint server for biology · 2026Article
- Neopterin as a Tool for Primate Ecoimmunology: Current Knowledge, Practical Application, and New Directions From Captivity to the Wild.American journal of primatology · 2025Review
- The Influence of Social Dynamics on Biological Aging and the Health of Historically Marginalized Populations: A Biopsychosocial Model for Health Disparities.International journal of environmental research and public health · 2024Review
- Differential effects of early life adversity on male and female rhesus macaque lifespan.Ecology and evolution · 2023Article
- Advancing methods for the biodemography of aging within social contexts.Neuroscience and biobehavioral reviews · 2023Review
- Early life adversities and lifelong health outcomes: A review of the literature on large, social, long-lived nonhuman mammals.Neuroscience and biobehavioral reviews · 2023Review
- Effects of intravenous infusion, vest wearing and repeated intravenous blood collection on clinical pathology parameters in cynomolgus monkeys (Macaca fascicularis).Experimental animals · 2023Article
- The biology of aging in a social world:insights from free-ranging rhesus macaques.bioRxiv : the preprint server for biology · 2023Article
- Cumulative exposure to maternal psychological distress in the prenatal and postnatal periods and atopic dermatitis in children: findings from the TMM BirThree Cohort Study.BMC pregnancy and childbirth · 2022Article
- The application of allostasis and allostatic load in animal species: A scoping review.PloS one · 2022Article
- The Symbiotic Relationship Between Scientific Quality and Animal Research Ethics.ILAR journal · 2021Article
- Biobehavioral organization shapes the immune epigenome in infant rhesus Macaques (Macaca mulatta).Brain, behavior, and immunity · 2021Article
- Assessment of medical morbidities in a rhesus monkey model of naturally occurring low sociality.Autism research : official journal of the International Society for Autism Research · 2021Article
- Prenatal Relocation Stress Enhances Resilience Under Challenge in Infant Rhesus Macaques.Frontiers in behavioral neuroscience · 2021Article
- Sociogenomic Approach to Wound Care: A New Patient-Centered Paradigm.Advances in wound care · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Early social stress has potent lifelong health effects. We examined the association of early stress in the attachment relationship (low maternal sensitivity, low MS), lower maternal social hierarchy rank, and greater frequency of group-level social conflict, with biomarkers of inflammatory stress response in plasma (IL-8, MCP-1 and CRP collected two hours after temporary separation from mothers and social groups) and risk for developing a common macaques disease outcome (infectious colitis) in 170 socially-housed rhesus monkeys. We controlled for gene-environment correlations by comparing cross-fostered subjects with infants reared by their biological mothers. Low MS predicted higher levels of pro-inflammatory cytokines and proteins at 3-4 months of age (F(3, 162) = 3.508, p = 0.002, partial eta
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.