ArticleNature communications2019
DNA-templated synthesis of biomimetic cell wall for nanoencapsulation and protection of mammalian cells.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Biomimetic zona pellucida-encapsulated islets for sustained glycaemic control in immunocompetent mice.Nature biomedical engineering · 2026Article
- Engineered cellular drug delivery: Strategies and applications.Materials today. Bio · 2025Review
- Review
- DNA-programmed responsive microorganism assembly with controlled patterns and behaviors.Science advances · 2025Article
- Responsive DNA artificial cells for contact and behavior regulation of mammalian cells.Nature communications · 2025Article
- Nucleic Acid Framework-Enabled Spatial Organization for Biological Applications.Chem & bio engineering · 2025Review
- Elastic Macroporous Matrix-Supported In Situ Formation of Injectable Extracellular Matrix-Like Hydrogel for Carrying Growth Factors and Living Cells.Macromolecular bioscience · 2024Article
- DNA framework signal amplification platform-based high-throughput systemic immune monitoring.Signal transduction and targeted therapy · 2024Article
- Anti-phagocytosis-blocking repolarization-resistant membrane-fusogenic liposome (ARMFUL) for adoptive cell immunotherapy.Science advances · 2023Article
- Synthetic Cell Armor Made of DNA Origami.Nano letters · 2023Article
- Nanoparticle-Decorated Biomimetic Extracellular Matrix for Cell Nanoencapsulation and Regulation.Angewandte Chemie (International ed. in English) · 2023Article
- Preparation, applications, and challenges of functional DNA nanomaterials.Nano research · 2023Review
- Alginate microfibers as therapeutic delivery scaffolds and tissue mimics.Experimental biology and medicine (Maywood, N.J.) · 2022Review
- Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine.Journal of nanobiotechnology · 2022Review
- Single-cell technologies: From research to application.Innovation (Cambridge (Mass.)) · 2022Review
- Synthetic DNA for Cell Surface Engineering: Experimental Comparison between Click Conjugation and Lipid Insertion in Terms of Cell Viability, Engineering Efficiency, and Displaying Stability.ACS applied materials & interfaces · 2022Article
- Engineered osteoclasts as living treatment materials for heterotopic ossification therapy.Nature communications · 2021Article
- Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy.Acta pharmaceutica Sinica. B · 2021Article
- Nanoarchitectonics on living cells.RSC advances · 2021Review
- Adaptable hydrogel with reversible linkages for regenerative medicine: Dynamic mechanical microenvironment for cells.Bioactive materials · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Mammalian cells are different from plant and microbial cells, having no exterior cell walls for protection. Environmental assaults can easily damage or destroy mammalian cells. Thus, the ability to develop a biomimetic cell wall (BCW) on their plasma membrane as a shield can advance various applications. Here we demonstrate the synthesis of BCW with a framing template and a crosslinked matrix for shielding live mammalian cells. The framing template is a supramolecular DNA structure. The crosslinked matrix is a polyelectrolyte complex made of alginate and polylysine. As the entire procedure of BCW synthesis is strictly operated under physiological conditions, BCW-covered mammalian cells can maintain high bioactivity. More importantly, the data show that BCW can shield live mammalian cells from not only physical assaults but also biological assaults. Thus, this study has successfully demonstrated the synthesis of BCW on live mammalian cells with great potential of shielding them from environmental assaults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.