Evidence map›Paper›PMID 31110155›Full record

ArticleGenetics2019

Mutational Landscape of Spontaneous Base Substitutions and Small Indels in Experimental

Anke Konrad, Meghan J Brady, Ulfar Bergthorsson, Vaishali Katju

Abstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. A complete human pancreatic cancer genome.bioRxiv : the preprint server for biology · 2026
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  10. Evolution of developmental bias explains divergent patterns of phenotypic evolution in two nematode clades.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anke KonradDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845.ORCID 0000-0003-3994-460X
Meghan J BradyDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845.
Ulfar BergthorssonDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845.ORCID 0000-0003-1419-1349
Vaishali KatjuDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77845 vkatju@cvm.tamu.edu.ORCID 0000-0003-4720-9007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental investigations into the rates and fitness effects of spontaneous mutations are fundamental to our understanding of the evolutionary process. To gain insights into the molecular and fitness consequences of spontaneous mutations, we conducted a mutation accumulation (MA) experiment at varying population sizes in the nematode

Indexed as

INDEL MutationMutation AccumulationMutation RateAnimalsCaenorhabditis elegansGenetic DriftPolymorphism, Single NucleotideSelection, Geneticbase substitutionCaenorhabditis elegansgenetic driftmutation accumulation lineselectionsmall indel

Identifiers

PMID31110155
PMCPMC6614903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.