Evidence map›Paper›PMID 31110136›Full record

ArticleRNA (New York, N.Y.)2019

Ribosome clearance during RNA interference.

Makena N Pule, Marissa L Glover, Andrew Z Fire, Joshua A Arribere

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Makena N PuleDepartment of MCD Biology, UC Santa Cruz, Santa Cruz, California 95064, USA.ORCID 0000-0001-5241-3040
Marissa L GloverDepartment of MCD Biology, UC Santa Cruz, Santa Cruz, California 95064, USA.
Andrew Z FireDepartments of Pathology and Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Joshua A ArribereDepartment of MCD Biology, UC Santa Cruz, Santa Cruz, California 95064, USA.ORCID 0000-0002-2467-7791
University of California, Santa Cruz · USStanford University · US

Funding

GENE REGULATION DURING EARLY DEVELOPMENT OF C. ELEGANSR01GM037706 · NIGMS · STANFORD UNIVERSITY · PI FIRE, ANDREW Z. · 1987 to 2018
$11.0M
Cellular Response to Genetic ChangeR35GM130366 · NIGMS · STANFORD UNIVERSITY · PI ANDREW Z. FIRE · 2019 to 2026
$4.8M
Mechanisms of Translational Surveillance in C. elegansR01GM131012 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Joshua Arribere · 2018 to 2026
$3.1M
Investigating the Ago Cleavage Independent Mechanism(s) of RNAiF32GM112474 · NIGMS · STANFORD UNIVERSITY · PI ARRIBERE, JOSHUA · 2014 to 2017
$141k
NIGMS NIH HHS F32 GM112474NIGMS NIH HHS R01 GM037706NIGMS NIH HHS R01 GM131012NIGMS NIH HHS R35 GM130366
6 · The paper itself

Abstract

In the course of identifying and cleaving RNA, the RNAi machinery must encounter and contend with the megadalton-sized ribosomes that carry out translation. We investigated this interface by examining the fate of actively translated mRNAs subjected to RNAi in

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsEndonucleasesRibosomesRNA, HelminthRNA InterferenceRNA, MessengerSequence Analysis, RNACaenorhabditis elegans ProteinsEndonucleasesRNA, HelminthRNA, MessengerC. elegansnonstopPELOTAribosomeRNAiSKI

Identifiers

PMID31110136
PMCPMC6633202
OpenAlexW2945252273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.