ArticleeNeuro
Properties of Individual Hippocampal Synapses Influencing NMDA-Receptor Activation by Spontaneous Neurotransmission.
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed.
- Linear ubiquitination of the NMDA receptor GluN2A subunit facilitates the GluN2B-to-GluN2A switch and synaptic maturation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture.Frontiers in synaptic neuroscience · 2026Article
- Structural and functional reorganization of inhibitory synapses by activity-dependent cleavage of neuroligin-2.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Loss of postsynaptic NMDARs drives nanoscale reorganization of Munc13-1 and PSD-95.bioRxiv : the preprint server for biology · 2024Article
- mGluR5 is transiently confined in perisynaptic nanodomains to shape synaptic function.Nature communications · 2023Article
- R-type voltage-gated CaCell reports · 2022Article
- Wnt-5a induces the conversion of silent to functional synapses in the hippocampus.Frontiers in molecular neuroscience · 2022Article
- Probabilities of evoked and spontaneous synaptic transmission at individual active zones: Lessons fromFrontiers in molecular neuroscience · 2022Review
- Regulation of NMDA Receptor Signaling at Single Synapses by Human Anti-NMDA Receptor Antibodies.Frontiers in molecular neuroscience · 2022Article
- Excitatory postsynaptic calcium transients atLearning & memory (Cold Spring Harbor, N.Y.) · 2021Article
- Review
- Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses.Frontiers in synaptic neuroscience · 2021Review
- Distance-dependent regulation of NMDAR nanoscale organization along hippocampal neuron dendrites.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons.PLoS biology · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
NMDA receptor (NMDAR) activation is critical for maintenance and modification of synapse strength. Specifically, NMDAR activation by spontaneous glutamate release has been shown to mediate some forms of synaptic plasticity as well as synaptic development. Interestingly, there is evidence that within individual synapses each release mode may be segregated such that postsynaptically there are distinct pools of responsive receptors. To examine potential regulators of NMDAR activation because of spontaneous glutamate release in cultured hippocampal neurons, we used GCaMP6f imaging at single synapses in concert with confocal and super-resolution imaging. Using these single-spine approaches, we found that Ca
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.