Evidence map›Paper›PMID 31110077›Full record

ArticleBioscience reports2019

Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using

Ji Wei Tan, Nuha Fahimah Wan Zahidi, Audrey Siew Foong Kow, Kuan-Meng Soo, Khozirah Shaari, Daud Ahmad Israf, Hui-Yee Chee, Chau Ling Tham

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Host immune response against DENV and ZIKV infections.Frontiers in cellular and infection microbiology · 2022
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ji Wei TanDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Nuha Fahimah Wan ZahidiDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Audrey Siew Foong KowDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Kuan-Meng SooDepartment of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Khozirah ShaariDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Daud Ahmad IsrafDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Hui-Yee CheeDepartment of Medical Microbiology and Parasitology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Chau Ling ThamDepartment of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia chauling@upm.edu.my.ORCID 0000-0002-9734-0372
Universiti Putra Malaysia · MYMonash University Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cells (MCs), a type of immune effector cell, have recently become recognized for their ability to cause vascular leakage during dengue virus (DENV) infection. Although MC stabilizers have been reported to attenuate DENV induced infection in animal studies, there are limited

Indexed as

AcetophenonesAnimalsbeta-N-AcetylhexosaminidasesCell DegranulationCell LineCell Line, TumorChlorocebus aethiopsDengueDengue VirusImmunoglobulin EKetotifenMast CellsMolecular StructurePhloroglucinolRatsTumor Necrosis Factor-alpha2,4,6-trihydroxy-3-geranylacetophenoneAcetophenonesbeta-N-AcetylhexosaminidasesImmunoglobulin EKetotifenPhloroglucinolTumor Necrosis Factor-alphaDENV-3in vitro mast cell degranulationketotifen fumarateRBL-2H3tHGA

Identifiers

PMID31110077
PMCPMC6549089
OpenAlexW2946639558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.