Evidence map›Paper›PMID 31109993›Full record

ArticleJournal of bacteriology2019

Unique Regions of the Polysaccharide Copolymerase Wzz

Steven M Huszczynski, Chelsea Coumoundouros, Phi Pham, Joseph S Lam, Cezar M Khursigara

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Characterization of two exoUBMC microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Lipopolysaccharide O-antigens-bacterial glycans made to measure.The Journal of biological chemistry · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Steven M HuszczynskiDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Chelsea CoumoundourosDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Phi PhamDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Joseph S LamDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada jlam@uoguelph.ca ckhursig@uoguelph.ca.ORCID 0000-0002-1822-1165
Cezar M KhursigaraDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada jlam@uoguelph.ca ckhursig@uoguelph.ca.ORCID 0000-0001-9263-7604
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outer leaflet of the outer membrane of nearly all Gram-negative bacteria contains lipopolysaccharide (LPS). The distal end of LPS may be capped with O antigen, a long polysaccharide that can range from a few to hundreds of sugars in length. The chain length of the polysaccharide has many implications for bacterial survival and consequently is tightly controlled. In the Wzx/Wzy-dependent route of O antigen synthesis, one or more Wzz proteins determine the chain length via an unknown mechanism. To gain insight into this mechanism, we identified and characterized important regions of two Wzz proteins in

Indexed as

Amino Acid MotifsAmino Acid SequenceBacterial ProteinsO AntigensProtein Conformation, alpha-HelicalProtein IsoformsPseudomonas aeruginosaSequence AlignmentBacterial ProteinsO AntigensProtein Isoformschain lengthlipopolysaccharideO antigenpolysaccharide co-polymerasePseudomonas aeruginosa

Identifiers

PMID31109993
PMCPMC6620407
OpenAlexW2946673440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.