Evidence map›Paper›PMID 31109921›Full record

ArticleG3 (Bethesda, Md.)2019

Computational Inference Software for Tetrad Assembly from Randomly Arrayed Yeast Colonies.

Nikita A Sakhanenko, Gareth A Cromie, Aimée M Dudley, David J Galas

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nikita A SakhanenkoPacific Northwest Research Institute, Seattle, WA 98122 aimee.dudley@gmail.com nsakhanenko@pnri.org.
Gareth A CromiePacific Northwest Research Institute, Seattle, WA 98122.ORCID 0000-0001-5265-1970
Aimée M DudleyPacific Northwest Research Institute, Seattle, WA 98122 aimee.dudley@gmail.com nsakhanenko@pnri.org.ORCID 0000-0003-3644-0625
David J GalasPacific Northwest Research Institute, Seattle, WA 98122.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe an information-theory-based method and associated software for computationally identifying sister spores derived from the same meiotic tetrad. The method exploits specific DNA sequence features of tetrads that result from meiotic centromere and allele segregation patterns. Because the method uses only the genomic sequence, it alleviates the need for tetrad-specific barcodes or other genetic modifications to the strains. Using this method, strains derived from randomly arrayed spores can be efficiently grouped back into tetrads.

Indexed as

SoftwareAllelesChromosome SegregationComputational BiologyGene Expression Regulation, FungalMeiosisRecombination, GeneticReproducibility of ResultsSpores, FungalYeastsdependency detectiongenetic segregation patternsinformation theoryyeast tetrad analysis

Identifiers

PMID31109921
PMCPMC6643883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.