Evidence map›Paper›PMID 31109778›Full record

ArticleInternational journal of cardiology2019

Right ventricular-vascular coupling ratio in pediatric pulmonary arterial hypertension: A comparison between cardiac magnetic resonance and right heart catheterization measurements.

K T N Breeman, M Dufva, M J Ploegstra, V Kheyfets, T P Willems, J Wigger, K S Hunter, D D Ivy, R M F Berger, U Truong

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  11. Exercise right ventricular ejection fraction predicts right ventricular contractile reserve.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021
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  17. Clinical Applications of Pressure-Volume Assessment in Congenital Heart Disease.Journal of the Society for Cardiovascular Angiography & Interventions
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

K T N BreemanCenter for Congenital Heart Diseases, Department of Paediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, the Netherlands. Electronic address: karelbreeman@gmail.com.
M DufvaDepartment of Bioengineering, University of Colorado, United States of America.
M J PloegstraCenter for Congenital Heart Diseases, Department of Paediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, the Netherlands.
V KheyfetsDepartment of Bioengineering, University of Colorado, United States of America.
T P WillemsDepartment of Radiology, University Medical Center Groningen, University of Groningen, the Netherlands.
J WiggerCenter for Congenital Heart Diseases, Department of Paediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, the Netherlands.
K S HunterDepartment of Bioengineering, University of Colorado, United States of America; Department of Paediatrics, Section of Cardiology, Children's Hospital Colorado, United States of America.
D D IvyDepartment of Paediatrics, Section of Cardiology, Children's Hospital Colorado, United States of America.
R M F BergerCenter for Congenital Heart Diseases, Department of Paediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, the Netherlands.
U TruongDepartment of Paediatrics, Section of Cardiology, Children's Hospital of Richmond of Virginia Commonwealth University, United States of America.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
NCATS NIH HHS UL1 TR002535
6 · The paper itself

Abstract

backgroundIn pulmonary arterial hypertension (PAH), right ventricular (RV) failure is the main cause of mortality. Non-invasive estimation of ventricular-vascular coupling ratio (VVCR), describing contractile response to afterload, could be a valuable tool for monitoring clinical course in children with PAH. This study aimed to test two hypotheses: VVCR by cardiac magnetic resonance (VVCR METHODS AND

resultsTwenty-seven patients diagnosed with idiopathic and associated PAH without post-tricuspid shunt, who underwent RHC and CMR within 17 days at two specialized centers for pediatric PAH were retrospectively studied. Clinical functional status and hemodynamic data were collected. Median age at time of MRI was 14.3 years (IQR: 11.1-16.8), median PVRi 7.6 WU × m

conclusionsNon-invasively measured VVCR

Indexed as

Pulmonary Arterial HypertensionVentricular Dysfunction, RightAftercareCardiac CatheterizationChildClinical Decision-MakingComparative Effectiveness ResearchDimensional Measurement AccuracyFemaleHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleSeverity of Illness IndexCardiac magnetic resonancePediatric pulmonary hypertensionRight heart catheterizationRight ventricular functionVentricular-vascular coupling ratio

Identifiers

PMID31109778
PMCPMC6710117

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.